A Guide to Alzheimer's Disease

Are you having memory problems that seem to go beyond the ordinary, or do you see this happening to someone you love? Are there other difficulties, like struggling to follow a conversation or find the right word, getting confused in new places, or botching tasks that once came easily? Everyone has these experiences sometimes, but if they happen regularly, they may be early signs of Alzheimer’s disease.

About 5.2 million Americans have Alzheimer’s disease. It is the sixth leading cause of death in the United States, and it is bound to become more common as the vanguard of the baby boom generation turns 65, the age at which Alzheimer’s becomes a major risk.

The information in this guide includes help for family members and caregivers, as well as for the individuals with Alzheimer’s. Because the disease is progressive, coping with it requires foresight and careful advance planning. This includes getting financial and legal documents in order, investigating long-term care options, and determining what services are covered by health insurance and Medicare. People in the early stages often can be partners in that planning.

Prepared by the editors of Harvard Health Publications in collaboration with John H. Growdon, M.D., Professor of Neurology, Harvard Medical School and Director, Memory and Movement Disorders Unit, Massachusetts General Hospital, 48 pages. (2009)

  • What is Alzheimer’s disease?
  • Is it forgetfulness or dementia?
    • Normal forgetfulness
    • Mild cognitive impairment
    • Dementia
  • Recognizing the symptoms
  • How the brain works
    • A macro view of the brain
    • A micro view of the brain
  • Risk factors for Alzheimer’s disease
    • Age and gender
    • Genetic factors
    • Other health problems
  • Possible protective factors
    • Medications
    • Alcohol
    • Education
    • Healthy habits
  • Diagnosing Alzheimer’s disease
    • Finding a physician
    • What to expect
    • The evaluation process
  • Is it Alzheimer’s or another dementia?
    • Reversible dementias
    • Irreversible dementias
  • The search for therapies
    • Drugs for memory and cognitive function
    • Medications for behavior problems
    • Therapies under investigation
  • Special Bonus Section: Caregiving: Day-to-day challenges and beyond
  • Anticipating the future
  • Planning ahead: Legal and financial matters
    • Legal decisions
    • Financial matters
  • Long-term residential care
    • Making the decision
    • Types of facilities
    • Evaluating a long-term care facility
  • Glossary
  • Resources

Alzheimer’s disease is a degenerative brain disorder that results in memory loss, impaired thinking, difficulty finding the right word when speaking, and personality changes. The following is a more detailed description of the disease’s warning signs:

Trouble remembering things. At first, only short-term memory may be affected. The individual may forget an appointment or the name of a new acquaintance. She may also forget where she left things, or she may leave things in odd places (for example, putting her shoes in the microwave). Eventually, long-term memory also is impaired, and the individual may not recognize family members.

Mood or personality changes. The person may suddenly become angry or sad for no apparent reason. Or someone who was social and outgoing may become withdrawn. The person may also become stubborn or distrustful. Depression also often accompanies Alzheimer’s disease, bringing such symptoms as loss of interest in a favorite hobby or activity, a change in appetite, insomnia or sleeping too much, lack of energy, and hopelessness.

Trouble completing ordinary tasks. Simple tasks that once caused no difficulty may become much more challenging. For example, the individual may forget how to use the oven, lock the door, or get dressed.

Difficulty expressing thoughts. It’s common for people with Alzheimer’s disease to have trouble with language. The individual may try describing an object rather than using its name—for example, referring to the telephone as “the ringer” or “that thing I call people with.” Reading or writing may also be impaired.

Impaired judgment. The individual might have trouble making decisions, solving problems, or planning. For example, he may no longer be able to balance a checkbook or pay bills.

Disorientation. We all know what it’s like to be driving and momentarily forget where we’re going. But those with Alzheimer’s disease may get lost in their own neighborhood. They may also lose track of dates and the time.

Unusual behavior. The individual may wander, become agitated, hide things, wear too few or too many clothes, become overly suspicious, engage in unsafe behaviors, or use foul language.

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