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Special Health Reports

Pathways to Longevity

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Pathways to Longevity: Science and strategies in pursuit of a longer, healthier life

Harvard Medical School’s new Special Health Report, Pathways to Longevity: Science and strategies in pursuit of a longer, healthier life, was created to help you stay strong, energized, and fully present for life’s most important moments. Thanks to advances in research and medicine, living longer has never been more accessible. But for most people, it’s not just about living longer—it’s about leading a healthy, high-quality life for as long as possible.

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While we can’t stop the clock, there’s a lot we can do to keep our bodies as healthy as possible as we get older.

Playing with your children or grandchildren, traveling, pursuing hobbies, and enjoying time with loved ones—all of these fulfilling activities require that you remain healthy, active, and independent. 

Climbing the stairs without hesitation. Carrying groceries with ease. Laughing freely without feeling tired halfway through the day. And most of all, keeping up with the people you love. 

This report won’t try to sell you on miracle cures or anti-aging gimmicks. Pathways to Longevity focuses on what science actually tells us about living better and longer. Some of the most powerful changes are simple and already within reach. 

Prepared by the editors of Harvard Health Publishing in consultation with Medical Editor , David Barzilai, MD, PhD, MBA, MS, DipABLM. Lecturer, Harvard Medical School; Trustee and Faculty, Geneva College of Longevity Science; Diplomate, American Board of Lifestyle Medicine, 50 pages. (2026)

What should you eat?

There is no single, perfect diet plan everyone should follow. A healthy dietary pattern (the sum of all the foods you eat on a regular basis) can be modified to fit one’s tastes, preferences, schedule, and cultural heritage. But all healthy dietary patterns have certain features in common: more plants and plant proteins (vegetables, fruits, beans, lentils, nuts, seeds, whole grains) and less animal foods (especially red and processed meats) and refined carbohydrates than the typical American diet. This pattern automatically increases intake of beneficial nutrients (fiber, vitamins, minerals, phytonutrients, and unsaturated fatty acids), while decreasing those that have proved detrimental to health (sodium, added sugars, and saturated fats).

To summarize the key tenets of good nutrition, experts at the Harvard T.H. Chan School of Public Health and Harvard Medical School developed the Healthy Eating Plate (see Figure 4, page 30). It recommends
the following at each meal:

Vegetables and fruits. Half of your plate (with a slightly greater proportion taken by vegetables). Aim for a colorful variety, but don’t include potatoes in this category.

Whole grains. A quarter of your plate. This includes whole grains like brown rice, oats, corn, and whole-grain foods made with them, such as pasta and bread. As an alternative to a grain-based choice, starchy vegetables (like potatoes and sweet potatoes) could be included in this section.

Healthy proteins. A quarter of your plate. Choose fish, poultry, and plant-based proteins such as beans, lentils, and tofu. Limit red meat and avoid processed meats.

Healthy plant oils. Enjoy in moderation, avoiding hydrogenated oils and other sources of saturated fat. (Keep in mind that the word “hydrogenated” will be found in an ingredient list, not on a product’s front label.)

Water (and coffee or tea). Make these your main beverages. Skip sweetened drinks and limit fruit juices to a small daily glass.

  • Living longer and better 
    • How long will you have? 
    • Lifespan vs. healthspan 
  • How well are you aging? 
    • Assessing biological age 
    • How health care providers measure aging 
  • Targeting aging at its roots 
    • The 12 hallmarks of aging 
  • Emerging interventions 
    • Medications under investigation 
    • Other potential interventions 
  • Supplements: Buyer beware 
    • The facts about popular supplements 
  • Eating to extend your healthspan
    • What should you eat? 
    • The power of plants 
    • Research-backed dietary patterns 
    • Should you cut calories? 
  • Movement and your healthspan 
    • Setting activity goals 
    • Fitting in fitness
  • Other key factors: Sleep, stress, and more 
    • Sleep
    • Stress
    • Mental health
    • Connections
    • Engaging your brain 
    • Happiness 
    • Purpose 
    • Alcohol 
    • Tobacco, nicotine, and other toxins 
  • Take action: Smart steps to extend your healthspan
    • Get serious about preventine health 
    • Stick to the science 

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