Immune and infectious diseases Archive

Chronic, low-level inflammation is just as important as cholesterol in causing clogged heart arteries. Cardiologists are calling for more widespread testing for inflammation, which is easily measured with an inexpensive blood test.

Autoimmune disorders that may involve skin symptoms include psoriasis, lupus, scleroderma, dermatomyositis, vitiligo, bullous pemphigoid, alopecia areata, lichen planus, autoimmune thyroid disease, celiac disease, rheumatoid arthritis, and sarcoidosis.

Physical activity improves physical and mental health, and walking is the simplest way to stay active. Walking for more than 10 minutes at a time may offer extra benefits, but all movement counts. For people over 60, 6,000 to 8,000 steps a day are optimal, regardless of walking speed.

An Indian-adapted Mediterranean diet includes vegetarian-focused meals flavored with an array of vibrant spices. The fiber-rich meals contain anti-inflammatory compounds that may provide heart-related health benefits. Healthy protein sources include legumes, featured in dishes such as chana masala (chickpeas in a tomato-based sauce) and dal (a soupy stew made from dried split lentils or peas). Tomatoes, eggplant, and peppers appear often in both the Mediterranean diet and the Indian-adapted version, as do leafy greens such as spinach.

Inflammaging is chronic, low-grade inflammation throughout the body that occurs with aging. It is believed to accelerate aging and contribute to more than half of all deaths worldwide by driving various age-related diseases such as arthritis, autoimmune conditions, heart disease, cancer, diabetes, and Alzheimer's disease. People can combat inflammaging through healthy lifestyle measures such as exercising, eating healthfully, controlling weight, managing stress, prioritizing sleep, and limiting alcohol and smoking.

Science has made astonishing progress in the past 60 years in many areas. Examples include the ability to repair certain defective genes, use stem cells to treat certain diseases, detect and fight many cancers, fight viruses with medications, make organ transplants work, and prevent disease with vaccines and lifestyle changes. Thanks to technological advances, doctors can also see clearly inside the body and use artificial intelligence to speed the development of new medications.

Daily nasal irrigation (also called nasal rinses) may reduce symptom severity and the duration of a cold. It can also relieve the congestion caused by sinus infections and allergies. It is unclear whether it can prevent colds. By means of a squeeze bottle, neti pot, or battery-powered system, saline (salt water) is inserted into one nostril and flows out the other. It's important to always use sterile water, meaning distilled or cooled boiled water. The rinse helps wash away mucus and some inflammatory chemicals, reducing the swelling that's responsible for congestion.

Shingles occurs when the dormant chickenpox virus reactivates, causing tingling, burning, and a painful, blistering rash. Shingles can affect anyone who has had chickenpox, with higher risk after age 50 and in people with weakened immunity. Diagnosis and treatment within three days of the rash appearing can shorten the illness and reduce severity. Most people recover completely from shingles, but there may be complications, such as post-herpetic neuralgia, which is pain that can be severe and long-lasting. Vaccination is the best way to prevent shingles and its complications.

Elderberry syrup or tea may help reduce the duration and severity of cold and flu symptoms. But the evidence for these benefits is uncertain, since the studies are small and most did not compare elderberry to standard treatments. Claims that elderberry products can prevent viral infections or boost immunity are unproven. Elderberry supplements appear to be relatively safe; in clinical trials, effects such as nausea, vomiting, or diarrhea were mild and rare.