Immune and infectious diseases Archive

If you've ever had food poisoning caused by Salmonella bacteria, you know it's unpleasant but typically goes away within two to three days. You may not know that these bacteria sicken more than a million people in the US each year - and can be deadly for some. You can take steps to avoid getting sick.

Sepsis causes or contributes to an estimated 20% of all deaths worldwide. The condition begins with an infection that spreads and over activates the immune system, which releases damaging inflammatory chemicals that lead to organ failure. Any infection can trigger sepsis, but those that begin in the lungs, urinary tract, gastrointestinal tract, or skin are more likely to do so. Older people are more susceptible to sepsis. The condition may be avoided by stopping bacterial or viral infections from occurring or worsening.

In October 2024, the CDC lowered the age for healthy adults to receive a pneumococcal vaccine to 50 from 65. It also recommends a second dose of the 2024-25 COVID vaccine for people 65 and older and immunocompromised people six months after their last dose.

Research has shown that men can have a higher risk for heart attacks and strokes if they suffer from certain medical conditions that might seem unrelated to heart disease. These conditions include erectile dysfunction, gum disease, peripheral artery disease, and urinary tract infections. Many factors that contribute to heart disease like inflammation and fatty deposits in the arteries are involved in these other conditions.

Some scientists believe that microbes might play a part in Alzheimer's disease development. They say it could be that certain viruses or bacteria that infect the brain aren't completely eradicated by the immune system, which leads to neuroinflammation and brain cell death. It could also be that microbes trigger the release of protein deposits-amyloid-beta plaques and tau tangles-which kill neurons, further increase neuroinflammation, and lead to more neuron death.