Alzheimer's Archive

The vast majority of older adults would want to know if they're in the early stages of Alzheimer's disease and would want a blood test to learn for certain, according to a 2025 poll. Advances in testing and treatment may fuel this desire for knowledge. There are pros and cons to knowing this information. People with an early Alzheimer's diagnosis can plan ahead, seek support, and may feel motivated to maintain their health. But the diagnosis may jeopardize their job or insurance coverage, as well as trigger anxiety or depression.

A 2025 study suggests that sleeping nine or more hours nightly is associated with worse cognitive performance, an effect that's stronger among people with symptoms of depression.

A 2025 study suggests that women who score highly on a brain health measurement incorporating physical, lifestyle, social, and emotional factors face lower stroke odds.

There are currently nine trials of vaccines for Alzheimer's disease under way. All of them are in people with mild Alzheimer's or with the pre-Alzheimer's condition called mild cognitive impairment. All of the vaccines are designed to encourage the immune system to remove protein deposits from the brain. Most experimental vaccines are given by injection; one being tested at Harvard Medical School uses a nasal spray. It will be several years before we know if any of them will work.

In a 2025 study, people with the healthiest diets and trimmest bellies at midlife had better brain connections and skills decades later, compared with people who ate the worst diets and had the most belly fat.

A 2025 study finds that a first-time transient ischemic attack (TIA) can lead to the same long-term decline in thinking and memory problems as a full-blown stroke. Experts suggest cognitive testing after a TIA. People who have TIAs should take extra care to address risk factors for heart attack and stroke, such as high blood pressure and high cholesterol. Exercising regularly and staying socially active may help ward off cognitive decline.

Menopausal hot flashes and night sweats, called vasomotor symptoms, are linked in research to higher odds of dementia and cardiovascular disease. But studies don't necessarily account for other health and lifestyle factors that influence brain and heart health. Women who are physically active and have a lower body mass index are less likely to become cognitively impaired. Disrupted sleep, which is common for women with vasomotor symptoms, may also contribute to cardiovascular and cognitive problems.

A 2025 study suggested that getting the shingles vaccine can significantly reduce the likelihood of developing dementia, especially among women.

Continuing to work in retirement can address many specific health needs of men as they age, such as stronger social connection, better cognitive health, and a greater sense of purpose. Regular work has been linked with higher rates of happiness and a lower risk for multiple health conditions. For men who don't want to re-enter the workforce, options like volunteering and mentoring can offer many of the same health benefits.