Mind & Mood
Some blood pressure drugs may lower dementia risk
In the journals
- Reviewed by Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing
Studies have shown a link between keeping blood pressure below 120/80 millimeters of mercury and a lower risk of developing dementia. For many older people, reaching that goal requires taking medication. To date, it has been unclear whether any particular drug or combination of drugs makes a difference in dementia risk.
A new study has found that blood pressure drugs that stimulate type 2 and 4 angiotensin II receptors in the brain may offer greater protection against Alzheimer’s disease and other dementias. These drugs include angiotensin-receptor blockers, such as valsartan (Diovan) and losartan (Cozaar); dihydropyridine calcium-channel blockers, like amlodipine (Norvasc); and thiazide diuretics, like hydrochlorothiazide (also known as HCTZ).
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About the Author
Matthew Solan, Executive Editor, Harvard Men's Health Watch
About the Reviewer
Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing
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