Medications and treatments Archive

Chronic pain sometimes originates in the pain-sensing nerves as well as injured body tissues.

Beta blockers can slow one's heart rate, which can make gauging intensity during exercise difficult. Monitoring your breathing is a good way to ensure you work out at an intensity that is sufficient and not too high.

Ketamine has been used for decades as an anesthetic, and in 2019 an inhaled version of it was approved by the FDA for treatment-resistant depression. But it is generally prescribed only when other treatments have not been effective.

Many medications claim to relieve migraine pain, but some are more helpful than others. In a large study looking at real-world data on 25 drugs, migraine sufferers rated the most and least helpful options.

Several types of "electroceutical" therapies use tiny zaps of electricity to help ease chronic pain. Transcutaneous electrical nerve stimulation (TENS) therapy and electroacupuncture are designed to work by interrupting pain signals being sent to the brain. Scrambler therapy is thought to work by changing pain information sent to the brain. Good candidates for such therapies are people with arthritis, neuropathy, neck or back pain, or pain from cancer treatment. Some people should stay away from electroceuticals, including those with any kind of implanted stimulation device, such as a pacemaker or bladder stimulator.

Pharmacies across the United States are struggling with budget cuts and staffing shortages. As a result, customers are sometimes experiencing delays in getting their prescriptions filled. Until pharmacies resolve their challenges, customers might need to work a little harder to get their medications promptly. One strategy that can help is ordering prescription refills early. If customers continue to have frequent delays at their pharmacies, they might consider switching their prescriptions to another store.

For people older than 75 who have heart disease already, or who are at increased risk of developing heart disease, there now is solid evidence that statins remain effective at lowering cholesterol and, more important, in reducing the risk of new or recurrent heart disease. For people older than 75 who have not been diagnosed with heart disease and are not at increased risk for developing it, the value of statins still is uncertain.

The weight-loss drug semaglutide is the first obesity treatment shown to help people live longer and have fewer cardiovascular problems. Developed as a drug for type 2 diabetes, semaglutide was first marketed as Ozempic; a higher-dose version for weight loss is called Wegovy. But because the drug is so popular, it can be hard to find, and it might not be covered by insurance.

A 2023 study suggests that taking low doses of amitriptyline, a tricyclic antidepressant also used to treat nerve pain, may be one of the best pharmacologic choices to help improve symptoms of irritable bowel syndrome.