Medications and treatments Archive

Many people end up taking a long list of medications when they might be able to safely reduce the number of daily pills. Reviewing medications with their specialists and primary care doctor can help determine which drugs may be reduced or perhaps discontinued.

Abruptly stopping a medication can be risky and even life-threatening. For example, suddenly discontinuing certain drugs can cause a rebound effect, meaning that symptoms or problems that were controlled—such as high blood pressure or heartburn—can return with a vengeance. Stopping some medications, such as prescription painkillers or antidepressants, might result in withdrawal symptoms. Before quitting any drug cold turkey, it's important to consult with a doctor to make sure that it's safe.

A newer class of medications used to treat type 2 diabetes called glucagon-like peptide-1 (GLP-1) receptor agonists has gained attention because of their impressive weight-loss results—in many cases, 10% to 20% of a person's body weight. Versions of two of these GLP-1 receptor agonists, liraglutide (Saxenda) and semaglutide (Wegovy), are FDA-approved for weight loss, even for people without diabetes. However, there isn't enough evidence to know whether these drugs might be beneficial or dangerous for people who are not diagnosed with diabetes or obesity.

Vasomotor symptoms, consisting of hot flashes and night sweats, affect 80% of women during the menopause transition and beyond. In May 2023, the FDA approved fezolinetant (Veozah) as the first nonhormonal medication designed specifically for vasomotor symptoms. Other medications deemed effective for hot flashes are prescribed off-label. They include selective serotonin reuptake inhibitors, oxybutynin, and gabapentin. But these drugs may lead to troublesome side effects. Women interested in hot flash relief should ask their clinicians for options that take into account their other symptoms.

Taking a blood thinner helps protect people at risk for dangerous blood clots that can lead to life-threatening conditions, such as a stroke or heart attack. But the medications increase the risk for uncontrolled bleeding. People taking the drugs should learn what to do in case bleeding occurs. For minor injuries, it's important to apply extra pressure until bleeding stops. For serious injuries, one should call 911 and apply as much pressure as possible to the wound until help arrives. People who take blood thinners and experience even minor injury from a fall or accident should automatically go to urgent care or the emergency department to get checked out, even if there is no apparent bleeding or trauma is observed.

Contrary to its reputation as an anti-aging supplement, human growth hormone is not effective at turning back the clock, and it may carry health risks. Commitment to a healthy diet and regular exercise is still the best formula for healthy aging.

Some medication instructions are vague and confusing. Examples include "take once daily," "take with food," and "take with water." When someone is unsure exactly how to take a medication, even if it's already been explained, it's best to ask for clarification. Ideally this happens when a doctor writes the prescription, but it's okay to call and ask later. It may also be helpful to ask a pharmacist for the directions, either when picking up a medication or on a later call.

The reason for weight gain isn't always as obvious as inactivity or a poor diet. Weight gain can stem from many other causes. For example, it might reflect age-related physiological changes such as muscle loss, poor sleep, or changes in sex hormone levels; underlying conditions such as diabetes or sleep apnea; side effects from taking certain medications, such as antidepressants or beta blockers; or possibly the effects of eating late at night or the makeup of gut bacteria. Recent or excessive weight gain warrants a visit to a doctor to help pinpoint the issue.

Men often confront obstacles that keep them from managing heart disease or lowering their risk for it. Harvard cardiologists share the advice they give patients who face challenges in the areas of weight loss, medication management, exercise, and diet. These include thinking about their future health goals, monitoring blood pressure, scheduling workouts, joining group weight-loss groups, and learning portion control for meals.

A nasal spray containing the experimental drug etripamil can quickly treat an abnormally fast heart rhythm called supraventricular tachycardia. The disordered rhythm occurs sporadically and can raise heart rate to as much as 200 beats per minute.