Heart Disease Archive

Getting vaccinated against influenza (flu), COVID-19, and pneumonia is especially important for people who have cardiovascular disease. The coughing and congestion that commonly occur with respiratory infections can make breathing more difficult, and the potential drop in oxygen puts added stress on the heart. Serious infections sometimes trigger sepsis, which happens when the immune system is overwhelmed or goes into overdrive, causing symptoms such as a rapid heart rate, very fast breathing, and low blood pressure. These complications can lead to a heart attack.

An inexpensive blood test that checks for a genetic variant of Lp(a)-a fatty particle similar to LDL cholesterol-may help clarify who might benefit from a daily low-dose aspirin, according to a 2025 review of study findings.

There are no medications to treat aortic stenosis (narrowing of the aortic valve), but several possibilities are currently being studied, including a class of drugs to treat diabetes and others that lower high lipoprotein(a) blood levels.

If a blood clot lodges in an artery or vein, it can choke off blood flow to the heart, brain, or lung. Often called blood thinners, anti-clotting drugs play a big role in treating heart disease. But they can cause minor (and sometimes serious) bleeding, ranging from nosebleeds to bleeding inside the brain. New solutions to balance clot prevention and excess bleeding are in the works, including low-dose drug combinations and new medications.

Menopausal hot flashes and night sweats, called vasomotor symptoms, are linked in research to higher odds of dementia and cardiovascular disease. But studies don't necessarily account for other health and lifestyle factors that influence brain and heart health. Women who are physically active and have a lower body mass index are less likely to become cognitively impaired. Disrupted sleep, which is common for women with vasomotor symptoms, may also contribute to cardiovascular and cognitive problems.

A 2025 study suggests that squeezing a week's worth of exercise (150 minutes) into just one or two days - a "weekend warrior" pattern - is linked to the same heart benefits as daily exercise.

Direct-to-consumer genetic tests can screen for rare heart conditions that arise from variants in a single gene (such as cardiomyopathies) as well as common conditions influenced by many thousands of gene variants (such as coronary artery disease). But because the results are not definitive, they can be challenging to interpret.

People with very high calcium scores (over 1,000) have a risk of heart attack or stroke similar to those who have already had a heart attack. They should take cholesterol-lowering drugs to bring down LDL levels and possibly undergo additional testing.

A 2025 research review suggested that women with certain gynecological disorders, such as polycystic ovary syndrome, endometriosis, heavy periods, and irregular menstrual cycles, have higher risks of cardiovascular and cerebrovascular disease.

A 2025 study found that a new type of medication may safely slow the progression of aortic stenosis (narrowing of the aortic valve) and delay the need for valve replacement.