Heart Disease Archive

The approach to certain blood tests appears to be shifting. Doctors might stop ordering routine vitamin D screenings for healthy people younger than 75; they might order a one-time combination of lipoprotein(a), C-reactive protein, and LDL (bad) cholesterol tests as a way to predict future heart problems; and they might rely less on standard ranges designated as "normal" in a complete blood count (CBC) test, and instead focus more on comparing someone's latest CBC results to previous CBC tests.

Cancer survivors are more likely to die of heart disease than from cancer-related complications. One reason is that certain cancer treatments can cause cardiovascular complications. But the two diseases share many root causes, including tobacco use and obesity, as well as diabetes and high cholesterol. Growing evidence suggests that people with heart disease may be more likely to develop cancer.

High levels of Lp(a)-a fatty particle similar to LDL cholesterol-may double or triple a person's risk of a heart attack. About one in five adults may have elevated levels, which also raises the risk of stroke and aortic stenosis. Unlike LDL, which rises with age and is influenced by diet and exercise, Lp(a) remains largely constant over a person's lifetime, so a one-time test suffices for screening. Lp(a) testing is becoming more common now that five promising new Lp(a) therapies are in development.

A condition caused by spontaneous genetic mutations in bone marrow cells, known as clonal hematopoiesis of indeterminate significance (CHIP), is linked to an increased risk of cardiovascular disease. Some of these mutations are clearly related to inflammation, a well-known contributor to the buildup of fatty plaque inside arteries. Experts hope that future research on CHIP will eventually lead to genetically directed therapies to address the condition.

People with type 2 diabetes may have greater protection from cardiovascular problems if they keep their systolic blood pressure (the first number in a reading) to 120 mm Hg or lower, according to a 2024 study.

A 2024 study found that people who follow a diet with a higher ratio of plant-based protein to animal-based protein may have a lower risk for cardiovascular disease and coronary artery disease compared with individuals who eat a lower plant-to-animal protein ratio.

Having type 2 diabetes doubles a person's odds of heart disease, and this risk may be present as early as 30 years prior to the diabetes diagnosis, according to a 2024 study. The findings support the long-held observation of the shared underlying causes of diabetes and heart disease. These include factors that contribute to both conditions, especially the tendency to accumulate fat in the middle of the body, known as abdominal obesity. This problem tends to occur in tandem with high blood pressure, unhealthy lipid levels, and elevated blood sugar-a cluster of signs and symptoms called metabolic syndrome.

Both the Mediterranean diet and vegan diet can help stave off heart disease. But while the Mediterranean diet is slightly more expensive than the standard American diet, a vegan diet is 19% lower in cost, according to a 2024 analysis.

Broken heart syndrome (officially known as takotsubo syndrome) causes symptoms similar to a heart attack. While intense emotional stress can trigger the condition, physical stressors such as surgery or severe illness are more common causes. Most cases occur in women, but proportion of cases recognized in men has risen in recent decades. Most people fully recover within weeks to months. But those who also have other serious health conditions may face a higher risk of dying within two months after being diagnosed with takotsubo syndrome.

Although doctors and patients rarely talk about it, cardiovascular disease and its treatment can affect sexual function. Atherosclerosis can affect arteries that supply blood to the genitals, and high blood pressure medication can cause sexual side effects. Certain medications used to treat common sexual issues (namely, erectile dysfunction drugs and some types of estrogen) may be unsafe for some people with heart disease.