Medical Tests & Procedures Archive

Abnormal results on a prostate-specific antigen (PSA) screening test for cancer are typically followed by a systematic biopsy. But systematic biopsies can be problematic, and researchers are seeking alternatives. A large European study provides encouraging evidence favoring a different approach that uses MRI instead of biopsy.

In 2024, the FDA approved a blood test called Shield as a screening method for colorectal cancer. The test detects 83% of colorectal cancers, but only 13% of precancerous polyps. The FDA approval means that now many insurance plans will pay for the test.

A study published in JAMA in July 2024 found that a blood test was accurate in diagnosing Alzheimer's disease, which causes steep declines in cognition and other aspects of health. The blood test is able to detect elevated blood levels of brain proteins that characterize the condition. While that's progress, doctors say it's not the test needed most. It would be more beneficial, they say, to have a test that accurately spots the developing disease long before it affects thinking. No such tests are here yet, but scientists are working to develop them.

Updated guidelines say adults don't need routine testing of vitamin D levels. However, they should aim for daily vitamin D intake of 600 international units (IU) until age 70, and 800 IU after that either through vitamin D-fortified foods or a supplement of up to 1,000 IU.

Men with high prostate-specific antigen (PSA) levels often get a biopsy of prostate tissue to check for cancer. The results of the biopsy are calculated to create a Gleason score, which helps doctors assess whether the cancer is low-, medium-, or high-risk. Based on that information, doctors may recommend that a man follow active surveillance (in which he monitors his PSA for changes) or begin cancer treatment.

Getting an electrocardiogram (ECG) prior to undergoing noncardiac surgery should be the exception rather than the rule. About half of surgeries are low-risk and pose very little danger for the heart. Asking about a person's symptoms during physical activity-for example, whether they can walk up a flight of stairs without feeling winded-is a better gauge of their risk than the findings from an ECG. But presurgical ECGs make sense for older, inactive people with heart disease. The results can reveal signs of reduced blood flow to the heart or an unstable electrical heart rhythm that may require treatment before surgery.

Abnormal Pap test results don't always indicate cervical cancer. Most abnormal findings result from the presence of human papillomavirus, or HPV. Typically, the next step is a colposcopy, a test that enables the doctor to look closely at areas that appear abnormal.