Medical Tests & Procedures Archive

A nonsurgical approach for replacing a damaged aortic valve, known as transcatheter aortic valve replacement (TAVR), has become very popular in recent years. But it may not make sense for people in their 60s, who are likely to need a second valve replacement later in life. The valves used in TAVR only last about 10 years, on average. In addition, diagnosing and treating coronary artery disease may be more challenging in people who've had TAVR. Also, the surgery to replace a failed TAVR valve is more complicated than regular valve replacement surgery. So people who are likely to need least one traditional valve surgery are better off having the surgery in their 60s rather than in their 70s. A TAVR can be done the second time around.

For the first time, consumers can order a blood screening for Alzheimer's disease. The screening looks for two types of brain proteins, one of which is associated with Alzheimer's. Doctors have concerns about the screening: it's not FDA-approved, there's little information about its accuracy, and it can take a few days to speak with a doctor about the results. By comparison, an official Alzheimer's diagnosis involves a comprehensive evaluation of someone's current and past health problems, physical and neurological exams, family history, blood tests to rule out hidden conditions that might be causing memory problems (such as vitamin B₁₂ deficiency), and imaging tests.

Taking supplements that contain high levels of biotin (vitamin B₇) can lead to falsely low or falsely high results on a troponin test, a blood test used to diagnose heart attacks.

Lynch syndrome is an inherited condition that predisposes people to colorectal, uterine, ovarian, and other forms of cancer. Genetic testing can pinpoint Lynch syndrome, and genetic counseling is also recommended. People with Lynch syndrome need frequent cancer screenings and should watch for symptoms. Women with Lynch syndrome are also advised to undergo risk-reducing surgery that removes the ovaries, fallopian tubes, and uterus between ages 35 and 40, unless a woman is planning another pregnancy.

Ejection fraction is the fraction (expressed as a percentage) of the blood that the heart "ejects" out to the rest of the body when it contracts. Low ejection fraction signals one form of heart failure. An echocardiogram is the standard test to measure ejection fraction.

For people with chronic coronary disease who do not have symptoms, new guidelines recommend against routine testing with cardiac CT angiography, echocardiography, and stress testing. The results are unhelpful—and in some cases harmful. Unclear results often general additional testing or unnecessary procedures, including some that expose people to radiation for no reason. In addition, the tests add expense without any corresponding benefit, and these costs are increasingly being passed back to patients, in the form of copayments or higher premiums.

A 2023 study found that an oral penicillin challenge in a doctor's office provides a simple method of determining true penicillin allergy.

A transurethral resection of the prostate is considered the gold-standard treatment for benign prostatic hyperplasia. But newer, less invasive procedures offer faster recovery times and fewer risks of complications. Earlier this year another new procedure won the FDA's approval.

Troponins, which are proteins found in heart muscle cells, are released in the bloodstream during a heart attack. Other conditions, such heart muscle inflammation and chronic kidney disease, can also cause troponin levels to rise.