Breast Cancer Archive

Preterm birth joins other pregnancy-related conditions as potential heart risk factors.

 Image: © metinkiyak/Getty Images

Preterm birth has long been known to bring health risks for the baby, but it may also bring risks for the mother. A study in the June issue of Hypertension shows that women who gave birth to a baby before 37 weeks of pregnancy were more likely to experience rising blood pressures later on compared to women who delivered closer to term. If they had this pattern, they were also more likely to show signs of coronary artery disease, which is associated with an increased risk of heart attack and stroke.

Because of the unique demands that pregnancy places on a woman's body, it may serve as a stress test for the female heart, says Dr. JoAnn E. Manson, the Michael and Lee Bell Professor of Women's Health at Harvard Medical School. In the May issue, we talked about how other pregnancy-related conditions — gestational diabetes, pre-eclampsia (a type of pregnancy-induced high blood pressure), and other pregnancy-related hypertensive disorders — can raise a woman's risk of developing cardiovascular disease. Preterm birth should now join that list, says Dr. Manson.

While as many as one in 10 American women is affected by endometriosis, it can take years to get a correct diagnosis because the symptoms may mimic other common conditions. And myths about this condition may keep some women from seeking help.

Experts say there's little evidence that low-dose aspirin therapy brings benefits, and there are some risks.

In recent years, there's been a lot of talk about the potential benefits, and risks, of a regular regimen of low-dose aspirin. While much of the discussion has centered on whether taking low-dose aspirin can head off cardiovascular disease, some of the focus has also been on breast cancer. Can regular doses of this over-the-counter pain reliever reduce your risk of this common cancer?

For a while there were hints that the evidence was leaning that way. Back in 2017, this area of research, while still inconclusive, was somewhat promising. For example, a 2017 study published in Breast Cancer Research found that among some 57,000 women, those who reported taking low-dose aspirin (81 mg) at least three times a week had a 16% lower risk of breast cancer over all and a 20% lower risk of a specific type of hormonally driven breast cancer.

News briefs

The pandemic may have you feeling reluctant to seek medical treatment. But when it comes to cancer care, even a short delay in treatment may lead to deadly outcomes, according to a review of 34 studies published online Nov. 4, 2020, by BMJ. Researchers evaluated treatment delay and survival in more than a million people who had cancer of the bladder, breast, colon, rectum, lung, cervix, or head and neck. Each four-week delay in treatment — whether surgery, radiation therapy, or medication (such as chemotherapy or immunotherapy) — was associated with an increase of 6% to 8% in the likelihood of dying during the study period. Scientists say delays of up to eight weeks and 12 weeks further increased the risk of death. For example, in women who delayed breast cancer surgery by eight weeks, there was a 17% increased death risk; women who delayed surgery by 12 weeks had a 26% increase. Keep in mind, there are lots of unavoidable reasons why cancer treatment might be delayed, such as not being strong enough to undergo procedures or scheduling issues at a treatment center. But if there isn't a good reason to delay, it's best to get treatment as soon as possible.

Image: FG Trade/Getty Images

Research we're watching

If you're looking forward to having some extra downtime after retirement, just make sure it doesn't bring more sitting-down time. A study published online Nov. 17, 2020, by the journal Occupational and Environmental Medicine found that on average, women saw a sharp increase in sedentary time — more than an additional 20 minutes each day — after they retired compared with when they were working. This is an unhealthy pattern that can lead to a higher risk for cardiovascular disease.

Researchers identified this trend by looking at data on nearly 700 people (nearly 85% of them women) from a Finnish study. Most of the participants worked in administrative roles or held professional positions before retiring at an average age of 63. To provide objective measurements of activity, the participants wore activity monitors continuously for a full week during their one or two years both before and after retirement. The spike in sedentary time occurred after retirement, and remained at the reduced level for the next two years or more following retirement. Men, by contrast, saw a gradual decline in their activity level over time, but no sudden spike after they left their jobs. So, if you're retiring in the near future, it may be worth keeping an eye on your activity level to make sure you don't slow down after you leave your job.

Maybe you're feeling tired and having trouble concentrating — or perhaps you've noticed changes in your hair or weight, or just feel blah. You might easily attribute these issues to other health problems, or to simply getting older. But these symptoms can be signs of a sluggish thyroid.

The thyroid is a butterfly-shaped gland in the neck. It produces the hormones that regulate metabolism. Low levels of thyroid hormone can cause a range of symptoms, including fatigue, constipation, dry skin, brittle nails, hair changes, aches and pains, and feeling down. Untreated, an underactive thyroid (hypothyroidism) can increase the chances of developing high cholesterol, high blood pressure, and heart disease.

Many studies have explored the relationship between hair dye use and risk of cancer or cancer-related death, with conflicting findings. In a recent study, researchers analyzed survey data from over 117,000 women collected over several decades regarding hair dye use and overall cancer risk.

Screening for colorectal cancer can lower mortality, but it varies in effectiveness and is not always possible to perform, so alternatives are needed. Researchers analyzing studies found evidence for regular use of low-dose aspirin, leading the US Preventive Services Task Force to recommend it for some people.

The pandemic may be making life harder for those in abusive relationships, but help is available.

A woman experiencing abuse at the hands of an intimate partner often feels isolated and alone. But the truth is, she has a lot of company. As many as one in three women in the United States has experienced intimate partner violence (IPV), which is violence involving a current or former spouse, partner, significant other, boyfriend or girlfriend, says Eve M. Valera, an associate professor in psychiatry at Harvard Medical School. This number includes women from all different ages and backgrounds.

Those who experience IPV may be left with lingering health effects, including mental health disorders such as anxiety, depression, or post-traumatic stress disorder. IPV is also linked to a number of physical symptoms and conditions, according to the federal Office on Women's Health, such as digestive problems, migraine headaches, arthritis, asthma, chronic pain, sexual problems, and heart problems. Another area of growing concern for many researchers is the potential for cognitive changes caused by traumatic brain injuries linked to abuse, says Valera.