Breast Cancer Archive

News briefs

First it was certain blood pressure and heartburn drugs; now some medications used to treat type 2 diabetes are being recalled because of cancer concerns. The FDA warned in late May and early June 2020 that some lots of extended-release metformin may contain unacceptable levels of N-nitrosodimethylamine (NDMA), a possible cancer-causing chemical. At least five manufacturers are now issuing voluntary recalls of the medications. But if you take extended-release metformin, don't just stop on your own. Not all extended-release metformin products are affected by the voluntary recalls, and stopping any medication that controls blood sugar can be very dangerous. The FDA advises that you check in with your doctor or pharmacist. Ask if your medication is affected by the recall; if so, ask if you should switch to another version of the drug.

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The discovery that the urinary tract has a microbiome analogous to the one in the digestive tract has led to research showing that in women with urinary incontinence, their urinary microbiome differs from those in women who do not have urinary incontinence.

Tips to help you treat this common skin condition.

You thought you left acne behind you in your teen years, but here you are at midlife with a breakout. But it might not be what you think. Rosacea is often mistaken for acne, and the condition, which most often begins after age 30, sometimes flares at menopause, says Dr. Suzanne Olbricht, an associate professor of dermatology at Harvard Medical School.

A common skin condition affecting some 16 million Americans, rosacea most often develops in people with fair skin who blush easily. Rosacea is sometimes mistaken for sunburn, a naturally ruddy complexion, or even an allergic reaction. It produces a number of skin problems, including

Research we're watching

A new tool to identify people who might be at higher risk for pancreatic cancer could help doctors find cases earlier, when they are most treatable. Researchers from the Harvard T.H. Chan School of Public Health created a risk model that did a better job than current models of finding people at high risk for the disease. It takes into account clinical and genetic factors as well as blood levels of biomarkers (substances that could potentially indicate disease). To test the model researchers used data from four large clinical studies. They applied the tool to 500 known pancreatic cancer patients and more than 1,000 people without cancer. The researchers then assessed how well the tool would have predicted the risk of pancreatic cancer. Pancreatic cancer, which is the third leading cause of cancer death in the United States, is challenging to treat because most people already have advanced disease when they are diagnosed. It's hoped that identifying people who are at high risk will eventually allow doctors to screen these individuals to find cancers when they are smaller and more curable.

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In the journals

Scientists continue to explore the health benefits versus risks of aspirin therapy. One new analysis suggests that taking aspirin may protect against several types of digestive tract cancers. The results were published online April 1, 2020, by Annals of Oncology.

Researchers examined 113 observational studies of cancer in the general population. They found that individuals who took aspirin regularly — at least one or two tablets a week — had significantly lower rates of cancers of the bowel, stomach, gallbladder, esophagus, pancreas, and liver, compared with people who did not take aspirin.

Ask the doctors

Q. I'm hoping to prevent urinary incontinence. Is there anything I can do?

A. Nearly half of all women experience some type of urinary incontinence during the course of their lives. It may not be possible to prevent all of these cases, which can be caused by pregnancy, childbirth, or hormonal shifts that occur around the time of menopause. Here are some strategies that may help to reduce your risk.

Ask the doctors

Q. I've heard that walking could reduce my risk of breast cancer. Is this true?

A. Yes, it's true. Walking is not only a great form of exercise to help keep your heart healthy, it could potentially reduce your risk of breast cancer. One 2013 study, published in Cancer Epidemiology, Biomarkers & Prevention, found that women who walked seven hours a week — an hour a day on average — had a 14% lower chance of getting breast cancer when compared with women who walked three hours a week or less. The benefit was seen even in women who were at higher risk for breast cancer, including those who were overweight or who were taking hormone therapy. It's not clear how walking helps, but experts speculate that physical activity might help keep the body's levels of estrogen and insulin in check. Both of these hormones can fuel breast cancer, so regulating them more effectively could reduce your risk.

Most people understand the risks of sun exposure, even if they do not regularly wear sunscreen, but getting younger people to pay attention to this concern can be difficult. A study chose a novel approach to this problem by appealing to teenagers’ vanity and focus on their appearance.