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Mind & Mood Archive

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Defusing the “Benadryl challenge”: Discussing danger with teens

Viral challenges encourage risky behavior in teens with potentially serious consequences. The reasons teens do things like this are rooted in the development process of the adolescent brain, and adults need to understand why such challenges appeal to teens in order to talk to them about why they aren’t safe.

Blood test could find Alzheimer’s disease before symptoms appear

In the journals

Researchers are close to finding early cancer with a blood test. They may soon do the same with Alzheimer's disease. A new blood test called p-tau217 has shown great promise in diagnosing people with the disease, according to findings published online July 28, 2020, by JAMA.

The test looks for a specific type of tau protein in the blood. In people with Alzheimer's, tau protein in the brain forms tangles. Accumulation of tau protein tangles along with beta-amyloid deposits is thought to play a key role in how the disease develops.

Happy holidays?

Here's how to cope when your usual traditions get uprooted.

The holiday season, like just about everything else this year, probably won't look the same as usual. Whether that means going to smaller gatherings without the usual relatives, quarantining when traveling, or staying home entirely, chances are something will be different this year thanks to the COVID-19 pandemic. For many who look forward to a full table at Thanksgiving or a big party on New Year's Eve, these changes are unwelcome, and frankly a little depressing.

In response, people may experience emotions ranging from guilt to loneliness to a feeling of disconnected sadness, says Dr. Hilary Connery, assistant professor of psychiatry at Harvard Medical School.

Stress-induced brain activity linked to chest pain from heart disease

Research we're watching

Doctors have long known that mental or psychological stress can lead to angina (chest pain or discomfort caused by inadequate blood to the heart). Now, new research reveals a direct correlation between angina and stress-related activity in the brain's frontal lobe. The study included 148 people with coronary artery disease with an average age of 62. All underwent brain and heart imaging tests done in conjunction with mental stress testing, which involved mental arithmetic and public speaking. Imaging tests were also done under "control" conditions, which featured simple counting and recalling a neutral event. Researchers monitored the participants for angina during the tests; they also assessed angina rates again after two years.

Activity in the inferior frontal lobe area of the brain during mental stress was linked to the severity of self-reported angina, both during the brain imaging and at the two-year follow-up. A better understanding of how the brain reacts to stress may be an important consideration for doctors who treat angina, according to the study's lead author. The study was published online Aug. 10, 2020, by the journal Circulation: Cardiovascular Imaging.

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