Medications and treatments Archive

Sinus problems are common, especially those caused by allergies, which affect some 40% of American adults. They often manifest as stuffiness, congestion, or a reduced sense of smell. Sinus problems most commonly fall into three categories: acute viral infections, allergy triggered inflammation, and chronic sinus infections.

In people with obesity, a high-dose weekly injection of the diabetes drug semaglutide caused a 15% weight loss and improved other heart-related risk factors. Semaglutide works by mimicking a substance called GLP-1, which is made naturally by the gut and the brain. It prods the pancreas to release insulin when blood sugar rises too high, reduces appetite, and makes people feel full following a meal.

A 2022 study found that among adults 65 and older who undergo major surgery, nearly one in seven dies within a year. Dementia or frailty greatly increase the odds of postoperative death.

Migraines, which affect nearly 40 million Americans, are likely vastly underdiagnosed and undertreated. Women are three times more likely to get migraines than men, and hormones appear to be a major trigger. Other triggers include stress, disrupted sleep patterns, hunger or dehydration, certain foods or medications, and bright lights or loud noise. Newer medications are more targeted and pose fewer side effects. They include CGRP (calcitonin gene-related peptide) blockers, more effective nasal sprays, and green light therapy.

Taking antihypertension drugs to lower blood pressure that also stimulate type 2 and 4 angiotensin II receptors in the brain may offer protection against Alzheimer’s disease and other dementias.

A growing number of adults ages 65 and older are turning to cannabis to treat and manage their pain. While many individuals endorse its effectiveness and some studies have supported its use for pain management, the science is still inconclusive. Doctors can’t prescribe cannabis like conventional medications, but in many states, they can recommend its use for certain conditions, including pain.

Taking regular afternoon naps for less than 60 minutes can improve mental alertness and increase productivity.

Napping for  more than 30 minutes each day may be associated with increased risks for health problems. Causes of excessive napping include boredom, poor sleep at night, underlying conditions such as anemia or depression, medication side effects, dehydration, or malnutrition. Treating underlying conditions, staying hydrated, eating a healthy diet, becoming more active, and practicing good sleep hygiene may help reduce prolonged nap times.

Some medications, such as eye drops or inhalers, can be used with gadgets that make taking them easier. The devices might be especially helpful for someone with shaky or weak hands. Examples of gadgets that might help include eye drop guides, injection aids, inhaler spacers, and tube squeezers. The guides can help improve one’s grip, aim, or ability to squeeze out medication. Having better control may help a person take the correct amount of the drug.

A gene editing technique that permanently shuts down a cholesterol-raising protein called PCSK9 is being tested in heart attack survivors with an inherited form of high cholesterol. The one-time infusion contains tiny particles that contain the editing tools, which travel through the blood to the liver and changes the cells that produce the protein. If early data show the treatment to be safe and effective, the therapy potentially could be used in people who have "garden variety" high cholesterol.