Heart Attack Archive


Genetic profiling for heart disease: An update

A polygenic risk score for heart disease is based on an analysis of more than three million common DNA variants and is expressed as a percentile. People can have zero, one, or two copies of any variant, each of which may either raise or lower the risk of coronary artery disease. Many of these variants occur in genes known to affect heart disease, such as those related to cholesterol, blood pressure, and blood clotting. Others aren't well understood and may provide targets for future research, potentially fueling new drug discovery efforts. For now, the potential benefits of this test are greatest for people under 50.

Low-dose aspirin linked to anemia

Older people who take low-dose aspirin every day may be more likely to develop anemia. Aspirin discourages blood clots, but the drug also blocks substances that help maintain and protect the delicate tissue lining the gastrointestinal tract. Long-term aspirin use can damage this protective layer, making bleeding more likely. Minor bleeding can go unrecognized and contribute to anemia, a condition marked by a reduced number of healthy red blood cells. People currently taking aspirin should check with their doctor to see if the practice still makes sense for them.

Testosterone therapy may be safe for men at risk for heart attack and stroke

A 2023 study suggests taking testosterone replacement therapy does not raise the risk for heart attacks or stroke among men with cardiovascular disease or a high risk for it, but it could increase the risk of atrial fibrillation, acute kidney injury, and pulmonary embolism.

Focusing on six food groups may help prevent cardiovascular disease

A 2023 study suggests eating enough of six categories of food common in popular heart-health diets is associated with a lower risk of cardiovascular disease, including heart attacks and strokes. The six groups are fruits, vegetables, legumes, nuts, fish, and dairy products.

Weather and air pollution linked to heart-related hospitalizations

Lower temperatures, high wind speed, atmospheric pressure, high precipitation, and high degrees of pollution may raise the risk of being hospitalized for serious heart-related conditions. Modeling these factors may help forecast future heart problems.

Statin alternative lowers heart-related deaths

The cholesterol-lowering drug bempedoic acid (Nexletol) can be a good alternative for people who can't take statins. A 2023 study found that compared with a placebo, bempedoic acid can lower the risk of heart attacks and related problems.

Heart attacks may speed cognitive decline

Accelerated cognitive decline may be more common after a heart attack, probably because the same factors that lead to narrowed heart arteries (the root cause of most heart attacks) can also cause tiny, silent strokes. An accumulation of these strokes shows up as bright areas (called white matter lesions) on an MRI scan. These lesions are markers of typical cognitive changes that occur with age. But people who have heart attacks likely have more white matter lesions and experience even greater cognitive decline.

Heart attacks strike in different ways

There are two different mechanisms by which most heart attacks happen. Both are related to insufficient blood flow to an area of the heart, most often secondary to fatty plaque buildup in coronary arteries. Chest pain remains the most common heart attack symptom, but others are often subtle, and the underlying process causing the heart attack can differ. It's important for people to recognize the different signs of heart attacks, so they know when to seek immediate medical care.

Calm your anxious heart

Anxiety disorders promote the stress response, which influences the same brain systems that affect cardiovascular functions.

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