Heart Attack Archive

A 2023 study suggests taking testosterone replacement therapy does not raise the risk for heart attacks or stroke among men with cardiovascular disease or a high risk for it, but it could increase the risk of atrial fibrillation, acute kidney injury, and pulmonary embolism.

Older people who take low-dose aspirin every day may be more likely to develop anemia. Aspirin discourages blood clots, but the drug also blocks substances that help maintain and protect the delicate tissue lining the gastrointestinal tract. Long-term aspirin use can damage this protective layer, making bleeding more likely. Minor bleeding can go unrecognized and contribute to anemia, a condition marked by a reduced number of healthy red blood cells. People currently taking aspirin should check with their doctor to see if the practice still makes sense for them.

A polygenic risk score for heart disease is based on an analysis of more than three million common DNA variants and is expressed as a percentile. People can have zero, one, or two copies of any variant, each of which may either raise or lower the risk of coronary artery disease. Many of these variants occur in genes known to affect heart disease, such as those related to cholesterol, blood pressure, and blood clotting. Others aren't well understood and may provide targets for future research, potentially fueling new drug discovery efforts. For now, the potential benefits of this test are greatest for people under 50.

A 2023 Harvard study found that regularly squeezing a week's worth of exercise (150 minutes) into just one or two days—a "weekend warrior" approach—is linked to the same heart-healthy benefits as daily exercise.

There are two different mechanisms by which most heart attacks happen. Both are related to insufficient blood flow to an area of the heart, most often secondary to fatty plaque buildup in coronary arteries. Chest pain remains the most common heart attack symptom, but others are often subtle, and the underlying process causing the heart attack can differ. It's important for people to recognize the different signs of heart attacks, so they know when to seek immediate medical care.

Accelerated cognitive decline may be more common after a heart attack, probably because the same factors that lead to narrowed heart arteries (the root cause of most heart attacks) can also cause tiny, silent strokes. An accumulation of these strokes shows up as bright areas (called white matter lesions) on an MRI scan. These lesions are markers of typical cognitive changes that occur with age. But people who have heart attacks likely have more white matter lesions and experience even greater cognitive decline.

Anxiety disorders promote the stress response, which influences the same brain systems that affect cardiovascular functions.

Research into the health benefits of alcohol has not provided a clear answer. Some findings suggest that alcohol helps protect against heart disease and lowers the risk of heart attacks and strokes, and drinkers tend to live longer than nondrinkers. Other studies say these benefits are less clear. If you don't drink alcohol now, there are no health reasons to start drinking. If you do enjoy it, it's best to have no more than 2 drinks in the same day.