Digestive Health Archive

A 2023 study of lab animals suggests that the population of microbes in an individual's gut may influence the risk of developing Alzheimer's disease. Researchers found that healthy lab rats developed signs characteristic of Alzheimer's disease when they were injected with gut microbe samples from people with Alzheimer's. Rats that received samples from the most severely affected Alzheimer's patients developed the greatest brain abnormalities and memory problems. Rats did not develop these problems when they were injected with samples from people who had no signs of the disease.

A small randomized trial in 2023 found that taking two 250-mg capsules of curcumin four times a day was as effective at relieving dyspepsia symptoms as taking one daily 20-mg dose of the heartburn medication omeprazole (Prilosec, Zegerid).

Virtually everyone carries the bacteria Clostridioides difficile, or C. diff. But half a million Americans a year develop a serious C. diff infection due to a gut microbiome imbalance. It disproportionately strikes people in hospitals and nursing homes, and can recur repeatedly.

Following a plant-based eating pattern and cutting back on highly processed foods can help promote a more diverse, healthier microbiome. A healthy gut microbiome may decrease inflammation that promotes heart disease. Most fruits, vegetables, beans, and whole grains are good sources of prebiotic fiber, which is broken down by gut bacteria to create short-chain fatty acids. These fatty acids are linked to lower inflammation and reductions in other heart disease risk factors.

"Regular" bowel movements can mean something different for each person. Some people have a bowel movement once or twice daily; for others, it's once or twice weekly. People should see a doctor if they notice a dramatic change in bowel habits or other symptoms, including fatigue, pain, unintended weight loss, bloody stool, or a change in stool consistency. People can promote digestion by maintaining a toileting schedule, heeding their body's signals, and using a toilet stool.

A 2023 study suggests that women who have used menopausal hormone therapy are significantly more likely to develop gastroesophageal reflux disease (GERD).

Eating two peeled kiwifruits per day may help ease constipation, according to a small randomized trial published in 2023. The effectiveness of eating kiwifruits was slightly greater than that of using a daily fiber supplement such as Metamucil or Fiberall.

In the US population as a whole, deaths from colon cancer have been declining, but in people under 50 that rate has increased. Most major medical organizations recommend screening beginning at age 45 for people at average risk.

Removing tonsils in childhood was once routine care for healthy children, but is no longer recommended. Why are some organs and glands — appendix, tonsils, adenoids and more — considered expendable and why do we have them if they're not needed?