Alzheimer's Disease Archive

Ask the doctors

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Q. A friend and I both recently had ear blockages caused by impacted earwax. Is this something that becomes more common with age, or is it just a coincidence?

A. It's not just a coincidence. Earwax blockages definitely increase with age. While blockages affect only 5% of healthy adults, they occur more often in older people, with 57% of nursing home residents experiencing this problem, according to the American Academy of Family Physicians.

Want to keep your mind sharp? Be aggressive about treating your high blood pressure.

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If you're like a lot of people, you probably think of your heart when you think about blood pressure. But you should also think about your mind.

"High blood pressure is not just a disease or condition. It's actually a risk factor. It's a risk factor for heart disease and stroke, and it's a risk factor for cognitive decline and dementia," says Dr. Natalia Rost, a stroke neurologist at Massachusetts General Hospital and associate professor of neurology at Harvard Medical School.

Research we're watching

A growing number of older adults are misusing opioids, according to a new report by the Substance Abuse and Mental Health Services Administration of the U.S. Department of Health and Human Services. The 2014 National Survey on Drug Use and Health showed that the percentage of adults ages 50 and older using heroin or misusing prescription opioids jumped from 1.1% to 2% between 2002 and 2014. In contrast, opioid use in adults ages 18 to 25 dropped from 11.5% to 8.1% over the same period.

Drug use can bring particular risks to the health and well-being of older adults because they are more likely than younger people to have other illnesses and often take medications that can interact with opioids, according Center for Substance Abuse Treatment. "These findings highlight the need for prevention programs for all ages as well as to establish improved evidence-based treatment, screening, and appropriate referral services," Dr. Kimberly Johnson, director for the Center for Substance Abuse Treatment, said in a written statement.

The purpose and engagement of a job you love can keep you healthy and connected.

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While many women dream of kicking back and relaxing into retirement, there's increasing evidence that in some cases, it's better for your brain and your health to keep your nose to the grindstone a little longer.

"The research to date is mixed, but it tends toward the positive — that is, for many people, there are health benefits to working longer," says Dr. Nicole Maestas, associate professor of health care policy at Harvard Medical School.

Research we're watching

Not only is obesity a risk factor for flu complications, but it might actually make the flu vaccine less effective, says a study published online June 6, 2017, by the International Journal of Obesity. Scientists at the University of North Carolina at Chapel Hill found that the flu shot provides less protection in people who are obese.

The study compared flu rates in 1,022 people during two recent flu seasons. All participants were vaccinated against the flu. The researchers looked at immune response to the vaccine and also tracked who went on to get the virus. They found that nearly 10% of obese participants got the flu, compared with 5% of their healthy-weight counterparts. This is bad news, because individuals with a body mass index of 40 or higher are also more prone to flu complications.

Can getting quality sleep help prevent the disease?

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A good night's sleep does more than rejuvenate you for the next day. It may help protect you against Alzheimer's disease. Research has begun to show an association between poor sleep and a higher risk of accumulating beta-amyloid protein plaque in the brain, one of the hallmarks of the disease.

"Observational studies have found that adults over age 65 with amyloid plaques in their brain have reduced slow-wave sleep, which is thought to play an important role in memory function, even though these people do not yet show signs of Alzheimer's, like memory loss and cognitive decline," says Dr. Brad Dickerson, associate professor of neurology at Harvard Medical School. "It may be that quality sleep could play a role in who may get Alzheimer's."

In the journals

If you get acute conjunctivitis, or pinkeye, you probably don't need antibiotic eye drops, suggests a study published online June 14, 2017, by Ophthalmology.

Pinkeye is caused by viral infection, allergy, or bacterial infection. Most people with pinkeye are prescribed antibiotic drops. However, a majority of cases are due to a virus or allergy, which do not respond to antibiotics. Antibiotic treatment can potentially delay healing and increase antibiotic resistance.

Watch out for unpasteurized products, and ask vendors about food safety.

There's something magical about strolling through a farmers' market on a crisp autumn morning. The fruit and vegetables seem fresher there than they do in a store — apples taste tarter, tomatoes seem redder and riper. It's a farm-to-table connection that puts you in touch with nature and the harvest.

Maybe that's partly behind the explosion of farmers' markets across the country, climbing from about 2,000 markets in 1994 to more than 8,600 today, according to the Farmers Market Coalition. "It's a great way to get fresh produce and try different foods you may not have come across before. But it should be enjoyed with caution," urges Dr. Simi Padival, an infectious disease specialist with Harvard-affiliated Beth Israel Deaconess Medical Center.

Exercising, maintaining good health, socializing, and learning new information may help keep you sharper, longer.

Everyone wants to live an active, vibrant life for as long as possible. And that goal depends on robust brain health. While we don't have a guaranteed way to prevent dementia, we do have increasing evidence that engaging in healthy lifestyle habits may help.

For example, a 2015 randomized controlled trial from Finland suggested that older adults with a number of healthy habits — such as eating a healthy diet, exercising regularly, and socializing — improved or maintained thinking skills and reduced the risk of cognitive decline.