Alzheimer's Disease Archive

The brain's fear center may trigger inflammation and lead to a heart attack. But stress reduction techniques can break the chain.

 Image: © Cardiology Division, Massachusetts General Hospital

A small, almond-shaped area deep inside the brain called the amygdala is involved in processing intense emotions, such as anxiety, fear, and stress. Now, a new brain-imaging study reveals how heightened activity in the amygdala may trigger a series of events throughout the body that raises heart attack risk.

"This study identifies a mechanism that links stress, artery inflammation, and subsequent risk of a heart attack," says study leader Dr. Ahmed Tawakol, an associate professor of medicine at Harvard Medical School. Earlier animal studies have shown that stress activates bone marrow to make white blood cells. These infection-fighting cells trigger inflammation, a process that encourages the buildup of fatty plaque inside artery walls. "But what we didn't know was, does this happen in humans? And what is the role of the brain?" he says.

Don't accept regular fatigue as part of aging.

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Weariness, tiredness, lack of energy. There are many ways to describe those times when you are so fatigued you can't do anything. Often you bounce back after a quick rest or a good night's sleep, but if fatigue is occurring more often and lasting longer, it could be a sign of something more serious.

"Men may chalk up fatigue to aging, but there is no reason you should battle ongoing fatigue," says Dr. Suzanne Salamon, a geriatric physician with Harvard-affiliated Beth Israel Deaconess Medical Center. "Everyone gets tired sometimes, and your endurance may decline with age — you may not move as fast and sometimes tire quicker — but you should never be too fatigued to enjoy an active lifestyle."

Hurting bodies and suffering minds often require the same treatment.

Pain, especially chronic pain, is an emotional condition as well as a physical sensation. It is a complex experience that affects thought, mood, and behavior and can lead to isolation, immobility, and drug dependence.

In those ways, it resembles depression, and the relationship is intimate. Pain is depressing, and depression causes and intensifies pain. People with chronic pain have three times the average risk of developing psychiatric symptoms — usually mood or anxiety disorders — and depressed patients have three times the average risk of developing chronic pain.

Removing a Speck From the Eye

Occasionally, an eyelash or speck of dirt gets into the eye and causes irritation. If tears that form do not wash out the object, it can sometimes be removed by pulling the upper eyelid down over the lower eyelid. The lashes of the lower eyelid may brush out any foreign object that is caught under the upper lid.

If this does not work, try either of the procedures described below.

Some people live long lives with no disease or serious illness. What can they teach you about healthy living?

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You won't live forever, but it may be possible to live a long and maybe disease-free life by following the lead of "wellderlies."

This is a term to describe a special group of people who have reached ages 90 to 100 without having any major health issue or disease. And if they do get sick, it often happens late in their life and a short period before death.

In preliminary research, sucralose and acesulfame potassium increased insulin levels, although more studies are necessary to determine whether they—or other artificial sweeteners—increase the risk of insulin resistance.

Despite the lack of a universally recognized therapy for nighttime leg cramps, a few approaches may be worth trying.

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Few things are more jarring to a night's sleep than shooting calf pains. If you have nocturnal leg cramps, you have lots of company. Although they can strike people at any time of life, they become more common with age. Among people over 60, almost half report having leg cramps, a third say they are awakened by cramps at night, and 15% report weekly episodes.

What causes leg cramps?

Studies suggest that adopting a sunnier outlook may improve your health and even extend your life.

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In these turbulent times, it's sometimes a struggle to maintain a glass-half-full view of life. But if you can, it may serve you well. A growing body of research links optimism—a sense that all will be well—to a lower risk for mental or physical health issues and to better odds of a longer life.

One of the largest such studies was led by researchers Dr. Kaitlin Hagan and Dr. Eric Kim at Harvard's T.H. Chan School of Public Health. Their team analyzed data from 70,000 women in the Nurses' Health Study who, in 2004, had answered questions about how they viewed their futures

The risk of developing stress incontinence or urge incontinence increases along with BMI and body fat percentage. Stress incontinence is also associated with declines in grip strength.

The relaxation response appears to manage stress and some chronic conditions at the deepest levels.

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Chronic stress takes a toll on the body: it contributes to everything from high blood pressure and heart disease to anxiety, digestive disorders, and slow wound healing. On the flip side, managing stress helps control many chronic conditions or reduce your risk for developing them. Strategies include regular exercise, a healthy diet, and better sleep. And one strategy in particular—eliciting the relaxation response—may enable you to manage stress right down to your genes.

The anti-stressor

Trigger the response