Heart attacks in women

Although hard-to-read heart attacks happen to both men and women, they are more common in women. One reason for this is that men's symptoms initially set the standard for recognizing heart trouble. Now a growing body of research shows that women can experience heart attacks differently than men.

Understanding sex differences in heart disease is important. Heart disease is the leading cause of death for women. Although it mostly affects older women, it isn't rare in younger women. One in 10 of all women who die from heart disease or a stroke are under age 65, and this age group accounts for one-third of heart- or stroke-related hospitalizations. Even so, younger women and their doctors don't necessarily suspect a heart attack even when all the signs are there.

In a survey of more than 500 women who survived heart attacks, 95% of them said they noticed that something wasn't right in the month or so before their heart attacks. Two most common early warning signs were fatigue and disturbed sleep. Some women, for example, said they were so tired they couldn't make a bed without resting.

Chest pain, a common early warning sign of heart trouble for men, was further down the list for these women, reported by about one in eight. Those who did have it tended to describe it as pressure, aching, or tightness in the chest, not pain.

Even when their heart attacks were under way, only about one-third of the women in this study experienced the "classic" symptom of chest pain. Instead, shortness of breath, weakness and fatigue, a clammy sweat, dizziness, and nausea topped the list.

One take-home message is that some women may get an early warning of an impending heart attack in the form of excessive tiredness, disturbed sleep, or shortness of breath. Paying attention to these symptoms and getting prompt diagnosis and treatment just might stave off a full-blown heart attack. Some men also have early warning signals, with chest pain being the most common.

The other message is that women and their doctors need to think beyond chest pain when it comes to what women experience as a heart attack blossoms. Instead of writing off shortness of breath, fatigue, cold sweat, dizziness, and nausea as signs of something that will pass, everyone needs to give these symptoms a second look.

Top 12 symptoms women reported experiencing the month before and during heart attacks.

Before attack

During attack

Unusual fatigue (71%)

Shortness of breath (58%)

Sleep disturbance (48%)

Weakness (55%)

Shortness of breath (42%)

Unusual fatigue (43%)

Indigestion (39%)

Cold sweat (39%)

Anxiety (36%)

Dizziness (39%)

Heart racing (27%)

Nausea (36%)

Arms weak/heavy (25%)

Arm heaviness or weakness (35%)

Changes in thinking or memory (24%)

Ache in arms (32%)

Vision change (23%)

Heat/flushing (32%)

Loss of appetite (22%)

Indigestion (31%)

Hands/arms tingling (22%)

Pain centered high in chest (31%)

Difficulty breathing at night (19%)

Heart racing (23%)

From Circulation, 2003, Vol. 108, p. 2621