Surgical treatments and procedures Archive

A heart disease diagnosis may trigger a bout of depression. But having depression can also leave people more vulnerable to heart disease. Some of the overlap stems from shared lifestyle factors, such as inactivity and an unhealthy diet. In addition to addressing those issues, other safe and effective ways to ease depression include working with a therapist, using a light box, and taking medications.

After common heart procedures or surgeries, medications to help prevent heart attacks and strokes are essential. These include a combination of drugs to prevent blood clots (which is known as dual antiplatelet therapy and usually taken for just one year); drugs to lower LDL cholesterol down to 70 milligrams per deciliter or lower; and drugs to keep blood pressure and blood sugar in a healthy range.

An inexpensive blood test that checks for a genetic variant of Lp(a)-a fatty particle similar to LDL cholesterol-may help clarify who might benefit from a daily low-dose aspirin, according to a 2025 review of study findings.

A 2025 analysis found that tricyclic antidepressants, the anticonvulsants gabapentin (Neurontin) and pregabalin (Lyrica), and serotonin-norepinephrine reuptake inhibitors, such as duloxetine (Cymbalta) were the most effective drug treatments for neuropathic pain.

As people get older, they may get clumsier because of multiple factors such as declining hearing and vision, loss of muscle, balance issues, and chronic health conditions. Addressing these issues can help people avoid injury from falls and other accidents.

There are currently nine trials of vaccines for Alzheimer's disease under way. All of them are in people with mild Alzheimer's or with the pre-Alzheimer's condition called mild cognitive impairment. All of the vaccines are designed to encourage the immune system to remove protein deposits from the brain. Most experimental vaccines are given by injection; one being tested at Harvard Medical School uses a nasal spray. It will be several years before we know if any of them will work.

In robotic surgery, a surgeon controls robotic instruments that perform the operation, based on what the surgeon sees on a TV monitor. This type of surgery has many advantages: it involves small incisions, better views inside the body, and better range of motion than human hands. A research letter published in the May 2025 issue of JAMA Neurology described how robots controlled by a distant surgeon could reach in, grab, and remove blood clots stuck in a brain artery, reducing the damage from a stroke.

The four types of anesthesia include local anesthesia, regional anesthesia, monitored anesthesia, and general anesthesia. Before getting anesthesia, one should ask the doctor which type of anesthesia will be administered, what its risks are, and if delirium is a high risk. One should also ask how to prepare for anesthesia in the days leading up to a procedure-whether medications might need to be temporarily halted, when to stop eating or drinking before surgery, and whether to schedule measures to help reduce delirium.

A 2025 randomized controlled trial found that GLP-1 receptor agonists, the blockbuster drugs approved to treat diabetes and obesity, boosted the walking ability of people with diabetes and peripheral artery disease (PAD) in the legs. The news is encouraging, since there are few effective treatments for PAD-reduced blood flow in the limbs that leads to pain with activity. However, it will take more evidence before doctors feel comfortable prescribing GLP-1s if a person only has PAD.