Genes Archive

Scientists are beginning to understand the natural biological processes that control aging, and they have made exciting discoveries about tinkering with the process. For example, they've been able to make aged cells act like brand-new cells in lab experiments; they've figured out how to make worms live five times as long as they normally would; and they've been able to keep mice from becoming obese and from developing diabetes, kidney failure, and heart failure.

Half of people who live to 85 will develop Alzheimer’s disease — a disturbing statistic. But research into a family in South America has revealed a gene mutation that appears to afford protection, and may lead to a way to treat or possibly even prevent the disease.

Clinical trials for drugs to stop or slow the progression of dementia have not been successful. A recent study attempted to determine how much influence, if any, genetic and lifestyle factors may have on the development of dementia.

Although the two conditions seem unrelated, Alzheimer’s and heart disease actually share a genetic link. People who have a certain gene variant have both a somewhat elevated heart disease risk and a significantly elevated Alzheimer’s risk. Fortunately, a recent study has suggested that when people know they have this variant, they’re more likely to make healthy lifestyle choices that benefit their heart — and what’s good for the heart is good for the brain.