Heart Health

Aldosterone overload: An underappreciated contributor to high blood pressure

Recent guidelines recommend broader screening for elevated levels of aldosterone, a hormone produced by the adrenal glands.

By , Executive Editor, Harvard Heart Letter
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A gloved hand holds two tubes of blood samples for testing, one is labeled aldosterone and the other is labeled renin. the hand is above a rack filled with many sample tubes with assorted color caps.

Primary aldosteronism was once considered a rare cause of high blood pressure. But experts now believe the condition is underrecognized and undertreated. “Up to 25% of people with resistant hypertension are thought to have primary aldosteronism,” says Dr. Anna Krawisz, a cardiologist at Harvard-affiliated Beth Israel Deaconess Medical Center. (Resistant hypertension refers to blood pressure that remains stubbornly elevated even when people take three or more blood pressure drugs, including a diuretic.) Between 5% and 10% of all people with high blood pressure may have primary aldosteronism, she adds.

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About the Author

photo of Julie Corliss

Julie Corliss, Executive Editor, Harvard Heart Letter

Julie Corliss has been the executive editor of the Harvard Heart Letter since 2013. She also writes for the Harvard Health Letter, Harvard Women’s Health Watch, and Harvard Men’s Health Watch, as well as for Harvard … See Full Bio
View all posts by Julie Corliss

About the Reviewer

photo of Anna Krawisz, MD

Anna Krawisz, MD, Contributor

Dr. Anna Krawisz is an instructor in medicine at Harvard Medical School and a cardiologist and vascular medicine specialist at Beth Israel Deaconess Medical Center (BIDMC). Her research interests include disparities in care for peripheral artery … See Full Bio
View all posts by Anna Krawisz, MD
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