Bones and joints Archive

A condition caused by spontaneous genetic mutations in bone marrow cells, known as clonal hematopoiesis of indeterminate significance (CHIP), is linked to an increased risk of cardiovascular disease. Some of these mutations are clearly related to inflammation, a well-known contributor to the buildup of fatty plaque inside arteries. Experts hope that future research on CHIP will eventually lead to genetically directed therapies to address the condition.

Rheumatoid arthritis (RA) affects two to three times as many women as men. Scientists are uncovering RA's potential genetic and hormonal underpinnings, which point to potential reasons why women are more vulnerable. The newest treatments, called Janus kinase (JAK) inhibitors, resulted from research that has teased out delicate differences in immune system pathways. They block numerous proteins that ramp up inflammation fundamental to RA. The wide array of drug options now available for RA help doctors personalize therapies to each patient.

Certain strategies can help people avoid flare-ups of diseases that seem to be affected by cold weather. For example, people with psoriasis can ward off dry skin (which causes flare-ups) by taking short, lukewarm showers, using a humidifier at home, and moisturizing with cream-based emollients. People with asthma should try to do outdoor activities during warmer parts of the day, take a puff of a rescue inhaler before going out, and wear a mask when outdoors. And people with arthritis can exercise and try heat therapy.

Heart-healthy Valentine's Day gift ideas include products and experiences designed to make it easier and more enjoyable to follow the key tenets of a healthy lifestyle: eating well, getting regular exercise, sleeping soundly, and managing stress. Examples include strawberries dipped in dark chocolate, a cooking class, custom-fit sneakers, luxury sleep products, and a subscription to a meditation app.

Hand pain or stiffness makes computer or smartphone use difficult. Strategies to combat this include stretching the hands and fingers, avoiding awkward hand positions when holding a smartphone or computer mouse, taking breaks, alternating the fingers that do the work, and taking breaks. Using certain tools can also reduce hand strain or pain. Such tools include voice-to-text features, a wide-grip stylus, a smartphone holder, gel-filled wrist rests, and a comfortable mouse (which might be bigger, smaller, or vertical) to keep hands from stretching too wide or gripping too hard.

Setting health goals can help people in their 50s avoid developing a chronic condition that can hamper healthy aging. Goals can include improving balance through various exercises; learning a new skill to improve brain sharpness; seeking age-appropriate cancer screenings, such as for colorectal, cervical, and breast cancers; prioritizing bone health by boosting calcium and vitamin D intake and weight-bearing exercise; maintaining muscle strength through strength and resistance training; and paying closer attention to diet.