Bones and joints Archive

For people who have both heart disease and arthritis, two of the main treatments-exercise and medications-require careful planning and attention. Joint pain makes certain types of exercise difficult, and commonly used drugs for both conditions can have potentially serious interactions.

An estimated six in 10 women will at some point experience symptoms from pelvic floor weakness. Risk factors include pregnancy (especially with vaginal delivery), chronic constipation, family history, smoking, aging, menopause, obesity, chronic coughing, and occupations involving heavy lifting. Women with pelvic floor weakness may experience signs such as leaking urine, having trouble using a tampon, being unable to fully empty their bladder or rectum, and feeling a bulge in their vagina.

Rheumatoid arthritis (RA) affects two to three times as many women as men. Scientists are uncovering RA's potential genetic and hormonal underpinnings, which point to potential reasons why women are more vulnerable. The newest treatments, called Janus kinase (JAK) inhibitors, resulted from research that has teased out delicate differences in immune system pathways. They block numerous proteins that ramp up inflammation fundamental to RA. The wide array of drug options now available for RA help doctors personalize therapies to each patient.

A condition caused by spontaneous genetic mutations in bone marrow cells, known as clonal hematopoiesis of indeterminate significance (CHIP), is linked to an increased risk of cardiovascular disease. Some of these mutations are clearly related to inflammation, a well-known contributor to the buildup of fatty plaque inside arteries. Experts hope that future research on CHIP will eventually lead to genetically directed therapies to address the condition.

Certain strategies can help people avoid flare-ups of diseases that seem to be affected by cold weather. For example, people with psoriasis can ward off dry skin (which causes flare-ups) by taking short, lukewarm showers, using a humidifier at home, and moisturizing with cream-based emollients. People with asthma should try to do outdoor activities during warmer parts of the day, take a puff of a rescue inhaler before going out, and wear a mask when outdoors. And people with arthritis can exercise and try heat therapy.

Heart-healthy Valentine's Day gift ideas include products and experiences designed to make it easier and more enjoyable to follow the key tenets of a healthy lifestyle: eating well, getting regular exercise, sleeping soundly, and managing stress. Examples include strawberries dipped in dark chocolate, a cooking class, custom-fit sneakers, luxury sleep products, and a subscription to a meditation app.