Weight loss and management Archive

A 2026 review of six studies found that people with diabetes or obesity taking GLP-1 medications were prone to developing a number of nutrient deficiencies, particularly in vitamin D, iron, and B vitamins.

People on a weight-loss regimen should aim to lose 1 to 2 pounds per week, which translates into eating 500 to 750 fewer calories each day than they expend. Losing weight faster often causes excess muscle loss and lowers metabolism, making it harder to burn fat.

Research suggests that people who stop taking GLP-1 weight-loss drugs typically regain all the weight they lost in under two years. To sustain their progress, these people should eat more protein, fiber, and healthy fats; eat on a consistent schedule; exercise; and prioritize sleep.

A 2026 study suggested that people who stop taking weight-loss medications rapidly regain weight and lose heart health benefits associated with the drugs.

Two proven therapies for treating obesity - GLP-1 drugs and bariatric surgery - can help people lose substantial amounts of weight. The approaches differ in their effectiveness, durability, side effects, cost, and insurance coverage.

People can prevent excessive muscle loss while losing weight by doing resistance training to build muscle, consuming enough protein, and slowing their weight-loss pace.