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FDA approves first pill for postpartum depression

The FDA approved the first pill for postpartum depression in August 2023. The fast-acting drug, zuranolone (Zurzuvae), is taken for just two weeks.

Lynch syndrome: Reclaiming power

Lynch syndrome is an inherited condition that predisposes people to colorectal, uterine, ovarian, and other forms of cancer. Genetic testing can pinpoint Lynch syndrome, and genetic counseling is also recommended. People with Lynch syndrome need frequent cancer screenings and should watch for symptoms. Women with Lynch syndrome are also advised to undergo risk-reducing surgery that removes the ovaries, fallopian tubes, and uterus between ages 35 and 40, unless a woman is planning another pregnancy.

Beyond appetite suppression

Semaglutide (Ozempic, Wegovy), which mimics a natural hormone called GLP-1, has become a popular obesity drug because it promotes dramatic weight loss. New evidence suggests this drug and others like it may also curb compulsions for things other than food. The drugs may also dampen cravings for alcohol, smoking, gambling, and excessive shopping by hampering activation of the brain's reward pathways. If further research confirms preliminary findings, the demand for GLP-1 drugs is likely to increase.

Stopping a medication? Check first, quit safer

Abruptly stopping a medication can be risky and even life-threatening. For example, suddenly discontinuing certain drugs can cause a rebound effect, meaning that symptoms or problems that were controlled—such as high blood pressure or heartburn—can return with a vengeance. Stopping some medications, such as prescription painkillers or antidepressants, might result in withdrawal symptoms. Before quitting any drug cold turkey, it's important to consult with a doctor to make sure that it's safe.

Understanding new weight-loss drugs

A newer class of medications used to treat type 2 diabetes called glucagon-like peptide-1 (GLP-1) receptor agonists has gained attention because of their impressive weight-loss results—in many cases, 10% to 20% of a person's body weight. Versions of two of these GLP-1 receptor agonists, liraglutide (Saxenda) and semaglutide (Wegovy), are FDA-approved for weight loss, even for people without diabetes. However, there isn't enough evidence to know whether these drugs might be beneficial or dangerous for people who are not diagnosed with diabetes or obesity.

Cannabis use disorder may raise surgical risks

A 2023 study suggests that regular cannabis users have higher risks before, during, and after surgery, including the risk of heart attack, stroke, acute kidney injury, breathing difficulties, and blood clots.

New help for hot flashes

Vasomotor symptoms, consisting of hot flashes and night sweats, affect 80% of women during the menopause transition and beyond. In May 2023, the FDA approved fezolinetant (Veozah) as the first nonhormonal medication designed specifically for vasomotor symptoms. Other medications deemed effective for hot flashes are prescribed off-label. They include selective serotonin reuptake inhibitors, oxybutynin, and gabapentin. But these drugs may lead to troublesome side effects. Women interested in hot flash relief should ask their clinicians for options that take into account their other symptoms.

Injuries and blood thinners: How to stop bleeding

Taking a blood thinner helps protect people at risk for dangerous blood clots that can lead to life-threatening conditions, such as a stroke or heart attack. But the medications increase the risk for uncontrolled bleeding. People taking the drugs should learn what to do in case bleeding occurs. For minor injuries, it's important to apply extra pressure until bleeding stops. For serious injuries, one should call 911 and apply as much pressure as possible to the wound until help arrives. People who take blood thinners and experience even minor injury from a fall or accident should automatically go to urgent care or the emergency department to get checked out, even if there is no apparent bleeding or trauma is observed.

Insider tips for a smooth recovery from cataract surgery

Early planning can help people recover well from cataract surgery. That planning can include reviewing post-procedure instructions in advance; investigating whether a simplified eye drops regimen is available and will be covered by insurance; learning the right way to use eye drops, and teaching a loved one to help with their application if necessary; and preparing to take a break from certain physical activities, such as bending over, lifting objects that are 10 pounds or heavier, cleaning, vacuuming, or doing laundry.

FDA approves new surgical treatment for enlarged prostates

A transurethral resection of the prostate is considered the gold-standard treatment for benign prostatic hyperplasia. But newer, less invasive procedures offer faster recovery times and fewer risks of complications. Earlier this year another new procedure won the FDA's approval.

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