Mind & Mood Archive

A 2025 study of 250 people found that the brain can tell the immune system to prepare for impending infection even before a microbe enters the body. Scientists asked volunteers to don virtual reality headsets that showed various virtual people approaching them. Some of those approaching appeared to be healthy and others appeared to be sick. Brain scans and blood tests showed that participants' brains activated their immune systems when a virtual sick person simply came near them.

Researchers have found that high blood pressure, diabetes, and smoking had the greatest association with the likelihood of a dementia diagnosis as people age. Managing these issues could offer protection.

People have a 50% chance of developing at least one mental health disorder by age 75, according to some research. Among men, the most common are alcohol use disorder, depression, and anxiety disorders, with social anxiety disorder being the most prevalent of those. Many men miss the early warning signs of these disorders, or when they do, they often try to push through, which can worsen the symptoms. But identifying when they might have a problem is the first step toward seeking help.

The vast majority of older adults would want to know if they're in the early stages of Alzheimer's disease and would want a blood test to learn for certain, according to a 2025 poll. Advances in testing and treatment may fuel this desire for knowledge. There are pros and cons to knowing this information. People with an early Alzheimer's diagnosis can plan ahead, seek support, and may feel motivated to maintain their health. But the diagnosis may jeopardize their job or insurance coverage, as well as trigger anxiety or depression.

A quarter of American adults live with a mental health disorder such as anxiety, depression, obsessive-compulsive disorder, or post-traumatic stress disorder. But more than half don't seek help. Internal and external barriers may stop them from getting the care they need. Internal barriers are emotions or excuses people make to avoid treatment. External barriers include cost or difficulty finding a provider who can meet someone's individual needs. To push past obstacles, people can investigate less-expensive mental health programs or reframe guilt-inducing thoughts.

In May 2025, the FDA approved the first blood test to detect the early stages of Alzheimer's disease. The test looks for several proteins associated with Alzheimer's disease. About 80% of the time, the blood test is either highly positive or highly negative, a result that's accurate more than 90% of the time. Doctors expect that the test will soon be covered by insurance. If that happens, the test will become the standard of care for people ages 55 and older with Alzheimer's signs or symptoms.

A 2025 study suggests that women who score highly on a brain health measurement incorporating physical, lifestyle, social, and emotional factors face lower stroke odds.

A 2025 study suggests that sleeping nine or more hours nightly is associated with worse cognitive performance, an effect that's stronger among people with symptoms of depression.

There are currently nine trials of vaccines for Alzheimer's disease under way. All of them are in people with mild Alzheimer's or with the pre-Alzheimer's condition called mild cognitive impairment. All of the vaccines are designed to encourage the immune system to remove protein deposits from the brain. Most experimental vaccines are given by injection; one being tested at Harvard Medical School uses a nasal spray. It will be several years before we know if any of them will work.

In a 2025 study, people with the healthiest diets and trimmest bellies at midlife had better brain connections and skills decades later, compared with people who ate the worst diets and had the most belly fat.