Cholesterol and lipids Archive

If a blood clot lodges in an artery or vein, it can choke off blood flow to the heart, brain, or lung. Often called blood thinners, anti-clotting drugs play a big role in treating heart disease. But they can cause minor (and sometimes serious) bleeding, ranging from nosebleeds to bleeding inside the brain. New solutions to balance clot prevention and excess bleeding are in the works, including low-dose drug combinations and new medications.

A 2025 randomized controlled trial found that GLP-1 receptor agonists, the blockbuster drugs approved to treat diabetes and obesity, boosted the walking ability of people with diabetes and peripheral artery disease (PAD) in the legs. The news is encouraging, since there are few effective treatments for PAD-reduced blood flow in the limbs that leads to pain with activity. However, it will take more evidence before doctors feel comfortable prescribing GLP-1s if a person only has PAD.

In a 2025 study of more than 420,000 participants followed for about 13 years, people who walked at a steady or brisk pace had up to a 43% lower risk for developing heart arrhythmias, compared with those who walked at a slow pace.

Getting a sufficient amount of sleep is vital for heart health, but sleep continuity, timing, and regularity may also be important. Irregularities in these lesser-known dimensions of sleep health are not considered problems unless they impair a person's ability to function and quality of life. But emerging evidence suggest these sleep issues may affect cardiometabolic health. A sleep diary can help uncover potential issues.

A 2025 study finds that a first-time transient ischemic attack (TIA) can lead to the same long-term decline in thinking and memory problems as a full-blown stroke. Experts suggest cognitive testing after a TIA. People who have TIAs should take extra care to address risk factors for heart attack and stroke, such as high blood pressure and high cholesterol. Exercising regularly and staying socially active may help ward off cognitive decline.

Ultraprocessed packaged foods and drinks contain thickeners, preservatives, and other additives to improve their taste, texture, appearance, and shelf life. But the high amounts of salt, sugar, and fat in these products are probably more concerning for a person's health. Foods like sugary drinks and processed meats are the worst culprits. Eating a diet focused on whole, plant-based foods automatically lowers processed food intake and provides heart-protecting nutrients such as fiber, vitamins, and minerals.

Wearable fitness trackers like smart watches offer measurable and motivating data for exercise routines and safety, especially for people with heart conditions. Features include movement reminders, step counts (a daily total of 4,000 to 7,000 steps is considered beneficial), heart rate zones for exercise intensity, and measurements of heart rate recovery and variability to assess overall heart health. These tools can help optimize workouts and reveal potential issues.

Meatless burgers-which include plant-based meat alternatives like Beyond Burger and Impossible Burger and veggie burgers-are healthy replacements for traditional hamburgers. Those with the lowest amounts of saturated fat and sodium are the best options.

The surge in heat waves and extreme heat poses serious health risks for everyone but is a particular worry for older adults. What can you do to manage heat-related risks, especially if you have existing health conditions or take certain medications?

Metabolic syndrome is defined as having at least three of the following: abdominal obesity, high blood triglyceride levels, high blood pressure, high blood sugar levels, and low HDL cholesterol levels. The condition significantly increases the risk for cardiovascular disease, diabetes, kidney disease, fatty liver disease, and sleep apnea. While each factor is problematic, the main driver is abdominal obesity, from visceral fat surrounding internal organs. The best way to reduce visceral fat is aerobic exercise, strength training, and a plant-based diet.