Prostate Cancer Archive

A PSA test can detect early-stage prostate cancer while it’s still asymptomatic, but some men are diagnosed with prostate cancer only after symptoms appear. The editor in chief of the Harvard Medical School Guide to Prostate Diseases answers questions about how doctors distinguish prostate cancer from other noncancerous problems affecting the prostate.

Men on active surveillance for low-risk prostate cancer might need treatment if their PSA levels start to rise. Doctors also measure PSA to check for recurring cancer in men who were already treated with surgery or radiation. But use of the test in such cases differs in important ways.

Every year, millions of men around the world get a prostate-specific antigen (PSA) test. Abnormal readings on the test suggest a man might have prostate cancer. But how should an abnormal result be interpreted?

High-resolution micro-ultrasound may be an efficient alternative to using MRI plus conventional ultrasound to guide prostate biopsies, according to a 2025 study. The micro-ultrasound method proved as accurate as MRI guidance, but requires fewer visits and costs less.

For men who choose prostate cancer screening, it begins with measuring prostate-specific antigen (PSA) in the blood. Scientists continue to explore strategies beyond PSA testing to identify men who should have biopsies because they are more likely to have intermediate or high-risk cancer. These strategies include other types of PSA measurements, urine tests for genes, new imaging methods and artificial intelligence that works to improve the accuracy and efficiency of MRI and biopsies.

The US Preventive Services Task Force recommends against screening for prostate cancer in men older than 70, but as life expectancy for this group increases and treatment options evolve, it's important for men to be aware of their options.

Most men with prostate cancer have low-grade cancer, meaning the cancer is unlikely to spread or affect quality of life or longevity. But men whose initial prostate biopsy shows an intermediate-risk or high-risk cancer, or those who began active surveillance for low-risk cancer but develop a rising PSA or new symptoms suggesting aggressive cancer, have several treatment options available. These include different combinations of radiation, surgery, androgen deprivation therapy, chemotherapy, immunotherapy, and anti-androgens.

Looking after a loved one who has prostate cancer can be overwhelming. Caregivers play crucial roles in supporting a patient's physical and psychological well-being. But what does that entail? Here's what to know about effective communication, day-to-day support, and taking care of yourself.

Roughly one in six men will be diagnosed with prostate cancer at some point in their lives, but these cancers usually aren't life-threatening. The least risky form of the disease occurs frequently with age, will not metastasize to other parts of the body, and it doesn't require any immediate treatment. So, should it even be called cancer?