Prostate Cancer Archive

Radiation therapy for prostate cancer used to involve weeks or months of treatment. Today, radiation delivery is moving toward higher doses given with fewer sessions over shorter durations. Results from a clinical trial show that the two types of therapy offer the same long-term benefits.

There are three main treatment options for men whose prostate cancer has grown and become more likely to spread: surgical removal of the prostate, radiation to destroy the cancer cells, and hormone therapy to slow the cancer's growth. One aspect of treatment men should consider is the possibility of side effects. Understanding how common they are and their potential consequences can help men with their treatment choices.

Abnormal results on a prostate-specific antigen (PSA) screening test for cancer are typically followed by a systematic biopsy. But systematic biopsies can be problematic, and researchers are seeking alternatives. A large European study provides encouraging evidence favoring a different approach that uses MRI instead of biopsy.

Men with high prostate-specific antigen (PSA) levels often get a biopsy of prostate tissue to check for cancer. The results of the biopsy are calculated to create a Gleason score, which helps doctors assess whether the cancer is low-, medium-, or high-risk. Based on that information, doctors may recommend that a man follow active surveillance (in which he monitors his PSA for changes) or begin cancer treatment.

The specialized cells of our immune systems help to keep us healthy and free of infectious diseases. Immunotherapies teach those same cells to recognize and destroy cancer. Researchers are reporting promising results with a different method that involves engineered cells studded with receptors that bind to specific targets on cancer cells.

Of the cancer screening tests for men, tests for colon cancer has the strongest evidence for benefit. Men who opt in for prostate cancer screening may have more options beyond PSA blood testing to more accurately identify aggressive cancers. Other screening tests such as full body scans have not been shown to improve outcomes.

A 2024 study found that a urine test that looks for cancer genes may help identify the most serious cases of prostate cancer among men with high levels of prostate-specific antigen (PSA). This could help many men with high PSA levels avoid biopsies.

Artificial intelligence (A.I.) has made significant strides in helping doctors better diagnose and treat prostate cancer. A.I. uses mainly software programs that apply complex computational algorithms to improve precision and efficiency in diagnosis, treatment, and management. Three areas where A.I. will likely have the most impact are examining prostate biopsies with greater insight, finding hard-to-see tumors on MRI images, and determining which men undergoing radiation may also benefit from androgen deprivation therapy.