Mind & Mood Archive

The brain's fear center may trigger inflammation and lead to a heart attack. But stress reduction techniques can break the chain.

 Image: © Cardiology Division, Massachusetts General Hospital

A small, almond-shaped area deep inside the brain called the amygdala is involved in processing intense emotions, such as anxiety, fear, and stress. Now, a new brain-imaging study reveals how heightened activity in the amygdala may trigger a series of events throughout the body that raises heart attack risk.

"This study identifies a mechanism that links stress, artery inflammation, and subsequent risk of a heart attack," says study leader Dr. Ahmed Tawakol, an associate professor of medicine at Harvard Medical School. Earlier animal studies have shown that stress activates bone marrow to make white blood cells. These infection-fighting cells trigger inflammation, a process that encourages the buildup of fatty plaque inside artery walls. "But what we didn't know was, does this happen in humans? And what is the role of the brain?" he says.

Don't accept regular fatigue as part of aging.

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Weariness, tiredness, lack of energy. There are many ways to describe those times when you are so fatigued you can't do anything. Often you bounce back after a quick rest or a good night's sleep, but if fatigue is occurring more often and lasting longer, it could be a sign of something more serious.

"Men may chalk up fatigue to aging, but there is no reason you should battle ongoing fatigue," says Dr. Suzanne Salamon, a geriatric physician with Harvard-affiliated Beth Israel Deaconess Medical Center. "Everyone gets tired sometimes, and your endurance may decline with age — you may not move as fast and sometimes tire quicker — but you should never be too fatigued to enjoy an active lifestyle."

Hurting bodies and suffering minds often require the same treatment.

Pain, especially chronic pain, is an emotional condition as well as a physical sensation. It is a complex experience that affects thought, mood, and behavior and can lead to isolation, immobility, and drug dependence.

In those ways, it resembles depression, and the relationship is intimate. Pain is depressing, and depression causes and intensifies pain. People with chronic pain have three times the average risk of developing psychiatric symptoms — usually mood or anxiety disorders — and depressed patients have three times the average risk of developing chronic pain.

Some people live long lives with no disease or serious illness. What can they teach you about healthy living?

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You won't live forever, but it may be possible to live a long and maybe disease-free life by following the lead of "wellderlies."

This is a term to describe a special group of people who have reached ages 90 to 100 without having any major health issue or disease. And if they do get sick, it often happens late in their life and a short period before death.

The relaxation response appears to manage stress and some chronic conditions at the deepest levels.

 Image: © XiXinXing/Thinkstock

Chronic stress takes a toll on the body: it contributes to everything from high blood pressure and heart disease to anxiety, digestive disorders, and slow wound healing. On the flip side, managing stress helps control many chronic conditions or reduce your risk for developing them. Strategies include regular exercise, a healthy diet, and better sleep. And one strategy in particular—eliciting the relaxation response—may enable you to manage stress right down to your genes.

The anti-stressor

Trigger the response

Studies suggest that adopting a sunnier outlook may improve your health and even extend your life.

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In these turbulent times, it's sometimes a struggle to maintain a glass-half-full view of life. But if you can, it may serve you well. A growing body of research links optimism—a sense that all will be well—to a lower risk for mental or physical health issues and to better odds of a longer life.

One of the largest such studies was led by researchers Dr. Kaitlin Hagan and Dr. Eric Kim at Harvard's T.H. Chan School of Public Health. Their team analyzed data from 70,000 women in the Nurses' Health Study who, in 2004, had answered questions about how they viewed their futures

Studies show smoking high-tar unfiltered cigarettes, as opposed to medium-tar filtered cigarettes, greatly increases your risk of lung cancer. So, cigarettes labeled as low-tar or ultra light are an even safer choice, right? Wrong. A study comparing the lung cancer risks of different types of cigarettes found this seemingly logical assumption is false.

The study six years and involved over 900,000 Americans over the age of 30. The researchers compared the risk of death from lung cancer among men and women who were smokers, former smokers, or had never smoked. When analyzed according to the tar rating of cigarette smoked, the results of the study showed the risk of lung cancer death was greatest for smokers of high-tar unfiltered cigarettes. The risk of lung cancer death was no different among smokers of medium-, low-, and very low-tar cigarettes.

Mind-bending puzzles aren't the only route to improving memory and reason. Activities that engage your emotions and senses may be even better.

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In the midst of promotions for commercial brain training programs to ward off age-related cognitive decline, a few studies are beginning to indicate that simple pleasures may be even more productive. You may find that doing one of the following is an easier and more rewarding way to boost your brain than doing computer-based exercises.

1. Care for a dog

3.Play with a child

Vascular dementia is a less prevalent type of memory loss that nonetheless affects many older men.

 Image: Mike Watson Images/Thinkstock

While Alzheimer's disease continues to be the most recognized type of dementia, older men should also be mindful about the second most common: vascular dementia.

In vascular dementia, memory problems result from damage to large and small blood vessels in the brain. It develops when cholesterol-clogged blood vessels can't deliver enough oxygen to the brain. Small blockages deprive some brain cells of oxygen, which causes a series of small strokes that kill brain cells. This can lead to episodes of confusion, slurred speech, and problems thinking or remembering.

Older adults who report feeling lonely had a greater risk of testing positive for high amyloid levels in the brain, a marker of Alzheimer’s disease, according to research from the Harvard Aging Brain Study.