Cholesterol and lipids Archive

A study published online Feb. 16, 2022, by the European Heart Journal suggests that the prevalence of statin intolerance is much lower than commonly cited. Instead of 50%, the study found that prevalence is 6% to 10%.

Heart attacks occur when a blocked coronary artery prevents blood flow to part of the heart. Cardiac arrest is caused by an electrical misfire that causes the heart to abruptly stop beating.

For most people, statins are still the best way to lower harmful LDL cholesterol. But two newer drugs may be promising additions or alternatives for those with stubbornly high LDL levels. Bempedoic acid, which lowers LDL by about 25%, works in a manner similar to statins but may help reduce muscle-related side effects seen with statins. Inclisiran interferes with a protein that's involved with regulating LDL production in the liver; it lowers LDL by about 50%.

For people in their 80s and beyond, the advice for preventing and treating heart disease is similar to that for young people, especially with respect to staying physically active. But octogenarians may need to adjust their medication regimens. Low-dose aspirin is not recommended after age 70, and doses of anti-clotting medications may need to be reduced. Some people may also need to dial back their blood pressure medications if they experience side effects such as dizziness.

People who follow a low-carbohydrate/high-fat diet for weight loss often eat high amounts of saturated fat. Even though saturated fat can contribute to cardiovascular disease, a 2021 study suggests that eating higher amounts might not be bad for heart health in the short term.

The American Psychiatric Association has recently added prolonged grief disorder to its official list of classified mental disorders. Someone may develop this disorder when someone close has died within the past 12 months. The person may experience intense longing for the deceased or preoccupation with thoughts about him or her. These feelings occur most of the day and nearly every day for at least a month. Recognizing the signs and seeking out help with talk therapy are the best approaches to help prevent it from evolving to depression.

Naturally occurring plant compounds called stanols can help reduce cholesterol. But they may not be found in large enough amounts in butter substitutes to reduce cholesterol levels in the body. The best way to lower is cholesterol is still by eating a plant-based diet with more fruits and vegetables and less processed foods, reducing consumption of saturated fat, and working to maintain a healthy weight.

Dietary fat can both help and hurt heart health, depending on the source. Eating adequate amounts of the "good" fats—monounsaturated and polyunsaturated—can help reduce cholesterol levels and lower blood pressure. "Bad" saturated fat found in many processed foods can have the opposite effect. Following heart-healthy diets like the Mediterranean and DASH diets and making small substitutions in daily eating habits can ensure people get the proper amounts of good fats.

Exercise may help to reverse some types of heart damage. Not only can workouts prevent heart problems, but it may help to improve conditions that may raise risk for cardiovascular events. A 2021 study, for example, showed that a yearlong exercise program helped improve heart health in people who were at increased risk for heart failure.