Alzheimer's Disease Archive

Medications called anticholinergics are used to treat a host of conditions—overactive bladder, depression, allergies, and Parkinson's disease. They usually aren't recommended for older adults because one of the most common side effects is confusion and difficulty reasoning. Early studies have also indicated that long-term anticholinergic use is associated with an increased risk of dementia, and a recent study by researchers at the University of Washington adds more evidence to support that connection. The results were published online Jan. 26, 2015, by JAMA Internal Medicine.

The researchers tracked almost 3,500 men and women ages 65 and older who were free of dementia. When they matched prescription data for the previous 10 years with the participants' health outcomes, they determined that using anticholinergics was associated with an increased risk of developing dementia. Moreover, dementia risk increased with the dosage of the drugs and the length of time they were used. While people who had taken these drugs daily for the equivalent of three months had no increase in risk, those who had used them for over three years had a 54% greater risk than nonusers.

Long trips come with an increased risk of blood clots deep in the leg veins, which can have serious complications.

Q. My doctor, an internist, just retired, and my health plan is asking me to designate a new primary care physician. I'm 75. Would there be advantages to choosing a geriatrician as my new doctor?

A. First, a disclaimer: I am a geriatrician. So my short answer is, "Yes, of course!" But my reasoned, unbiased answer would be, "It depends." If you are a generally healthy 75-year-old woman, a family physician or internist will be able to take excellent care of you. Geriatricians are trained to care for older adults with complex illnesses and are expert in managing the care of people who are frail. Improving your ability to function, and the quality of your life, are the guiding principles of geriatric medicine. We are expert at managing complexity and uncertainty, working with families, and caring for people with serious illnesses who are approaching the end of life. A geriatrician would be a good choice if you have physical or cognitive impairment, if you take a lot of medications, or if your friends and family are involved in your medical care. For people who have several medical problems, we emphasize the role of patient and family preference in making medical decisions, with the patient's goals as our primary focus.

Few women realize how common pelvic prolapse is—and how easily treated. Here are five things you should know.

By Dr. Anne Fabiny, Editor in Chief, Harvard Women's Health Watch

Using an iPad or other backlit electronic tablet in the hours before bedtime not only prevents you from falling asleep, it may also affect your alertness the next day, according to a report published in the Proceedings of the National Academy of Sciences, Dec. 22, 2014. Researchers at Harvard-affiliated Brigham and Women's Hospital found that the light emitted by the devices reset the body's circadian clock, which synchronizes the daily rhythm of sleep to daylight. As a result, people reading e-books took longer to fall asleep and were less alert the next morning than when they read print books instead.

During the two-week study, 12 men and women read digital books on an iPad for four hours before bedtime each night for five consecutive nights. They also followed the same routine using printed books. When they read the iPad, participants were less sleepy before bedtime but were less alert the following morning, even after eight hours of sleep.

Q. Do the protective effects of alcohol extend to dessert wines and liqueurs, or do those have too much sugar?

Exercise, eat a healthy diet, and manage blood pressure and cholesterol to lower your odds.

Keep hydrated, and empty your bladder often to stave off these risky infections.

Poor sleep is linked to high blood pressure, diabetes, obesity, and heart disease. Now a study published in Neurology Dec. 10, 2014, suggests that people with conditions that rob them of oxygen and deep sleep are more likely to have changes in the brain that may lead to dementia. Researchers say conditions such as emphysema and sleep apnea reduce the amount of oxygen in the blood during sleep, which can lead to silent, undetectable "ministrokes." Researchers also found that people who spend less time in deep sleep, called slow-wave sleep, are more likely to have loss of brain cells than people who spend more time in slow-wave sleep. Slow-wave sleep is important in processing new memories and remembering facts. The researchers noted that past evidence has shown that using a continuous positive airway pressure (CPAP) machine for obstructive sleep apnea may improve cognition, even after dementia has developed. "Sleep quantity and quality are important to maintain optimal health and prevent disease," says sleep expert Dr. Lawrence Epstein, an instructor in medicine at Harvard Medical School. "By getting enough sleep, you ensure that you are getting all the types of sleep, which is necessary to maintain proper functioning."