Alzheimer's Disease Archive

A fainting spell can be inconsequential, or it can signal a serious health issue. It's important to learn why you faint.

Many procedures require anesthesia, and which of the four types you have can affect your recovery.

If you've ever had a tooth filled without Novocaine, you know the difference anesthesia can make. Anesthesia—whether it numbs your mouth or puts you into a full sleep—is designed to keep you comfortable during a procedure that otherwise might be hard to tolerate physically, emotionally, or both. "We have four goals: to see that you have no pain, that you're drowsy or unconscious, that your body is still so that the surgeon can work on it, and that you aren't left with bad memories of the procedure," says Dr. Kristin Schreiber, an anesthesiologist at Harvard-affiliated Brigham and Women's Hospital.

There are four basic kinds of anesthesia—local, which is typically administered to numb a small area; regional, which numbs a larger area, like your hand, arm, or foot; neuraxial (spinal or epidural), which is injected near the spine and numbs the lower half of your body; and general, which works in the brain to render you completely unconscious and unable to sense pain. The type used depends upon the procedure you're having, your state of health, and, often, your preferences.

Researchers from the biotechnology company Biogen have reported that a new drug reduced the amount of amyloid plaques—the brain deposits associated with dementia—and slowed cognitive decline in people with early Alzheimer's disease. They presented the report March 20, 2015, at the International Conference on Alzheimer's and Parkinson's Diseases in Nice, France.

The researchers studied 166 people ages 50 to 90 who had been diagnosed with mild Alzheimer's. The participants were randomly assigned to receive either a placebo or one of four different doses of the drug aducanumab—an antibody that attaches to amyloid deposits and turns the immune system on them.

Harvard researchers Joshua Hartshorne and Laura Germine have added to the growing body of research indicating that, in some respects, our cognitive function is improving, not declining, as we age. Their report, published online March 15, 2015, by Psychological Science, indicates that our vocabulary skills keep improving past retirement age.

The researchers wanted to understand how and when reasoning and memory change over the life span as a basis for distinguishing normal from abnormal aging. They recruited 48,000 volunteers of all ages and had them complete online tests that measured brain processing speed, memory, emotional intelligence, and vocabulary.

Music has charms to soothe a savage breast, as the 17th-century poet William Congreve wrote. In fact, music might soothe your heart by relaxing your arteries, a small study hints.

Researchers measured arterial stiffness in 20 healthy young adults before and after they listened to 30 minutes of classical music, rock music, or nothing (as a control). They used a technique called carotid-femoral pulse wave velocity (PWV). This measures the time it takes for the pulse to travel to the carotid artery in the neck versus the femoral artery in the leg. Longer pulse times suggest stiffer arteries, which translates to a higher risk of cardiovascular problems. Higher "wave reflections" (another measure of artery health) are also linked to heart disease risk.

Stay well when caring for a loved one by maintaining your physical and emotional health. Caring for yourself means you'll be able to care for another.

Q. Why is my doctor checking me for tuberculosis? I thought that was eradicated long ago

A. It would be wonderful if tuberculosis (TB) had been eradicated long ago, but unfortunately that's not the case. It is true that the annual number of new cases in the United States has been dropping over the past 20 years; in 2013, there were about 9,500 new cases. However, around the world, particularly in developing nations, TB remains a huge problem. In 2013, there were nine million new cases of TB, and 1.5 million deaths from TB, in the world.

Excessive sun exposure can cause damage that shows up many years later.

It may boost the effect of your current medication.

If your weather forecaster warns about a heat wave this summer, take it seriously. A study by Harvard researchers found that people with certain conditions were at an increased risk of winding up in the hospital during periods of high heat. Their work was published Dec. 23, 2014, in The Journal of the American Medical Association.

Researchers analyzed hospitalization rates for specific diseases among 23 million Medicare beneficiaries between 1999 and 2010. What sent older adults to the hospital most often during a heat wave? Heatstroke, fluid and electrolyte disorders, kidney failure, urinary tract infections, and sepsis (a dangerous blood infection). For some diseases, the risk of hospitalization was elevated for up to five days after a heat wave day, suggesting that preventing and treating heat-related illnesses is crucial both during and after a heat wave.