Alzheimer's Disease Archive

Infections from a drug-resistant fungus have been occurring around the world for the past decade. It's not cause for panic, but it's wise to understand the facts and ways to protect yourself.

Ask the doctor

Q. When we lose memories, do we lose them forever? A friend told me they may still be in our brains.

A. Our memories are stored inside nerve cells in our brains, often in multiple cells that communicate with each other. Each nerve cell looks a little like a tree, with a trunk, branches and, ultimately, little "twigs" (called spines). The spines of one cell communicate with those of another cell by releasing chemicals.

Ask the doctor

Q. I think I have heartburn, but I hear that what feels like heartburn is sometimes a more serious condition. How do I know if I have heartburn?

A. You've asked an important question. "Heartburn" describes symptoms caused by the reflux of stomach acid up into the esophagus (the tube that carries food from the mouth down to the stomach). It is a burning sensation. You can feel it high in the abdomen, just below the bottom of the breastbone, or underneath the middle of the breastbone in the chest. In other words, despite the word "heart" in the word "heartburn," real heartburn comes not from the heart, but from the stomach and esophagus.

Arthritis, bunions, and gout can be disabling. Here are common fixes to stay mobile.

Aching hips, knees, and shoulders are common, and over time can lead to immobility. But so can an aching big toe. The joint at the base of the big toe — called the metatarsophalangeal or MTP joint — is the part of the toe that is affected.

What's the MTP joint?

The MTP joint connects the first long bone (metatarsal) in the forefoot to the first bone of the big toe (phalanx). The joint bends with every step you take, so that you can push off and let the other leg move forward. But the MTP joint takes a beating during that process: for a brief moment as you push off, the MTP joint supports half of your body weight.

News briefs

Many people use psychological techniques to help them cope with chronic pain. But which approach is best? A study published Jan. 31, 2019, in the journal Evidence-Based Mental Health offers insight. Researchers analyzed 21 randomized studies focusing on the effect of either cognitive behavioral therapy (CBT), to redirect pain-related thoughts and behaviors, or mindfulness-based stress reduction (MBSR), combining yoga and meditation to build awareness and acceptance of moment-to-moment experiences (including pain). The result: There was no clear winner. Both approaches reduced pain and depression and improved physical functioning compared with usual care or no care. The authors say the findings are important, since CBT is considered the go-to psychological technique for chronic pain. But MBSR should be considered as an additional tool, they suggest. Want to try it? Many hospitals, universities, and meditation centers offer MBSR programs. You can also search for MBSR videos and classes online.

On call

Q. After I have a bowel movement I sometimes get quite weak and have to lie down until the feeling passes. Why does this happen and is it cause for concern?

A. The sensation you are describing is most likely due to a reflex called a "vasovagal reaction." Here's what I mean.

Learning to "belly breathe" helps ease your body's response to stress and tension.

The average person takes between 17,000 and 23,000 breaths per day, but there is a good chance we don't always breathe the right way. Chalk it up to how we deal with stress.

"When we feel something as a threat, our fight-or-flight response automatically kicks in," says Dr. Katherine Rosa, with the Harvard-affiliated Benson-Henry Institute for Mind Body Medicine. "Our breathing becomes more rapid and shallow and our hearts beat faster, all of which prepares us to run away from the threat."

Peripheral artery disease is serious but preventable.

As people get older, they sometimes shrug off painful cramping in their calves when they walk as a sign of age or overexertion. But it can be a symptom of a more serious condition known as peripheral artery disease, or PAD.

PAD is a condition in which fatty deposits collect in arteries outside the heart — most commonly in the legs — and reduce blood flow in that part of the body. Doctors used to think PAD mostly affected men, but when researchers began to include more women in their studies, they learned that the condition is just as common in women, affecting one in every 10 women over age 50 and one in every five over age 60, says Dr. Aruna Pradhan, a cardiologist and assistant professor of medicine at Harvard Medical School.

Running for 15 minutes a day or walking for an hour reduces the risk of major depression, according to a recent study.

It may be possible to outrun depression, according to a study published online January 23 by JAMA Psychiatry.

"We saw a 26% decrease in odds for becoming depressed for each major increase in objectively measured physical activity," says study author Karmel Choi, a clinical and research fellow at the Harvard T.H. Chan School of Public Health. "This increase in physical activity is what you might see on your activity tracker if you replaced 15 minutes of sitting with 15 minutes of running, or one hour of sitting with one hour of moderate activity like brisk walking."

ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. 

Q. Does the acne drug, isotretinoin (Accutane), cause depression and suicide, or are psychiatric risks from the Accutane side effects exaggerated?