Vitamins & Supplements Archive

Iron supplementation may be all it takes to reduce symptoms of restless legs syndrome. But many doctors don't know about it.

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People with restless legs syndrome (RLS) experience an overwhelming need to move the legs, particularly at night or as they fall asleep. But a simple treatment that may help reduce RLS symptoms is often overlooked as a potential first line of defense.

"The concern is that people are being started on medications first when iron might be a valuable treatment. It's simple, with relatively few side effects," says Dr. John Winkelman, an RLS specialist at Harvard-affiliated Massachusetts General Hospital.

News briefs

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Omega-3 fatty acid supplements may help ease anxiety symptoms in people diagnosed with a range of physical and mental health problems, according to a review published in the Sept. 14, 2018, JAMA Network Open. The report pooled findings from 19 different studies and included 1,200 people. Most of the studies compared omega-3 supplements to a placebo. Taken together, the studies included people with a range of health problems, including heart attacks, attention deficit disorder, substance abuse, depression, and Parkinson's disease, as well as some groups without any specific clinical diagnosis. Researchers found that people who took high doses of omega-3s (up to 2,000 mg a day) seemed to have the most reduction in anxiety symptoms. Omega-3 fatty acids, which are usually derived from fish oil, have a number of biological effects in the body. Brain membranes contain a high proportion of these fats, and human studies suggest that a lack of omega-3s in the brain may induce various behavioral and psychiatric disorders. For now, it's too soon to recommend high-dose omega-3 supplements for treating anxiety. Larger trials testing the supplements (both alone and combined with standard treatments) are needed, the study authors say.

Research we're watching

Do you know someone who is using a supplement for weight loss, muscle building, or sexual enhancement? You might want to recommend a dose of caution. An analysis published on October 12 by JAMA Network Open found that many of these supplements contain unapproved and potentially dangerous pharmaceutical ingredients. From 2007 to 2016, FDA reviewers detected contaminants in 776 dietary supplements, produced by 146 different companies. Contaminants included sildenafil, which is the generic form of the drug Viagra; sibutramine (Meridia), a weight-loss drug taken off the market in the United States in 2010; and anabolic steroids or steroid-like substances. And 20% of products contained more than one unapproved ingredient.

These supplements could prove harmful for those who take them because their ingredients may interact with other medications or cause problems for people with underlying health conditions.

Most lack evidence of any health benefit — and some contain stimulants that could affect your heart.

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Of the nearly $37 billion Americans spend on dietary supplements each year, about two-thirds are for vitamins and minerals. The rest are pills, powders, and tinctures that contain various substances isolated from an array of sources — mainly plants but also animals and microorganisms.

Why are these products so popular? Some people believe that our food supply has been stripped of important nutrients, so they take supplements to replace what's "missing" (although many foods are already fortified to replace vitamins that are destroyed during processing). Others feel that Western medicine relies too heavily on pharmaceuticals and prefer to take natural substances instead. (However, a number of common drugs are derived from plants.)

Vitamins don't seem to reduce cardiovascular risks, according to a new report.

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There may be reasons to take a multivitamin, but improving your cardiovascular health is not one of them, says a report in the July 10 issue of Circulation: Cardiovascular Quality and Outcomes. The authors found that for the average person, taking a multivitamin supplement didn't help prevent cardiovascular problems, such as heart attacks and strokes.

The findings were based on a review of general population studies conducted from 1970 to 2016, involving more than two million people. Researchers looked for associations between multivitamin supplementation and cardiovascular outcomes. But they weren't able to find any links.

Most older adults take some kind of over-the-counter dietary supplement. But are these products right for everyone?

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Over-the-counter dietary supplements are big business — more than 90,000 products generate about $30 billion every year in the United States. Older adults make up a big part of these sales, too. A survey of almost 3,500 adults ages 60 and older published Oct. 1, 2017, in The Journal of Nutrition found that 70% use a daily supplement (either a multivitamin or individual vitamin or mineral), 54% take one or two supplements, and 29% take four or more.

But are these pills good medicine, or a waste of money?

Research we're watching

Wondering if that herb or herbal supplement is safe and effective? A new app can tell you. The National Center for Complementary and Integrative Health has introduced a new app called HerbList, which provides research-based information on various herbal products.

The app, which is available free on the Apple App store and Google Play store, is designed to give consumers important details on the safety and effectiveness of some of the most popular herbs and herbal supplements. While marketers may claim these products bring health benefits and are safe, that might not always be the case. This app can help you sort through the claims to determine what's real — and what's not.

On call

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Q. I take fish oil supplements for heart health, but now I hear they aren't helpful. What's the truth?

A. Fish intake remains an important part of a healthy diet, but the enthusiasm for fish oil supplements has been dampened by several recent studies that showed no benefit for a variety of conditions.