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Lowering blood pressure: How low should you go?

Blood pressure that is
neither too low nor too high nets better health.

Image: Thinkstock

The dangers of hypertension are well documented, but low blood pressure levels can cause problems, too.

To lower stroke risk, be sure to get this B vitamin

Green vegetables and citrus fruits are good natural sources of folate.

If you're among the one in three American adults with high blood pressure, be sure you're getting enough of the B vitamin known as folate. Doing so may lower your odds of having a stroke, a new study suggests.

Ask the doctor: Do I need a tuberculosis test?

Q. Why is my doctor checking me for tuberculosis? I thought that was eradicated long ago

A. It would be wonderful if tuberculosis (TB) had been eradicated long ago, but unfortunately that's not the case. It is true that the annual number of new cases in the United States has been dropping over the past 20 years; in 2013, there were about 9,500 new cases. However, around the world, particularly in developing nations, TB remains a huge problem. In 2013, there were nine million new cases of TB, and 1.5 million deaths from TB, in the world.

Did youthful fun in the sun put you at risk for an eye condition now?

It's never too late to protect your eyes against sun damage. Look for sunglasses that block 95% to 100% of both UVA and UVB rays.

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Excessive sun exposure can cause damage that shows up many years later.

Adding a diuretic to your blood pressure drug

Diuretics can augment the blood pressure-lowering effects of other drugs, such as ACE inhibitors.

Image: Thinkstock

It may boost the effect of your current medication.

Pay attention to heat wave warnings this summer

If your weather forecaster warns about a heat wave this summer, take it seriously. A study by Harvard researchers found that people with certain conditions were at an increased risk of winding up in the hospital during periods of high heat. Their work was published Dec. 23, 2014, in The Journal of the American Medical Association.

Researchers analyzed hospitalization rates for specific diseases among 23 million Medicare beneficiaries between 1999 and 2010. What sent older adults to the hospital most often during a heat wave? Heatstroke, fluid and electrolyte disorders, kidney failure, urinary tract infections, and sepsis (a dangerous blood infection). For some diseases, the risk of hospitalization was elevated for up to five days after a heat wave day, suggesting that preventing and treating heat-related illnesses is crucial both during and after a heat wave.

How you can make colonoscopy prep easier

Colonoscopy saves lives, and adequate prep is essential for a successful colonoscopy. New laxative preps are making the process easier to tolerate.

Special MRI scan could identify stroke risk in people with atrial fibrillation

Atrial fibrillation is a heart rhythm disorder that affects millions of people. It can lead to potentially disabling or deadly strokes. Researchers from Johns Hopkins University School of Medicine adding motion-tracking software to standard MRI heart scans of 149 men and women with atrial fibrillation. The scans revealed specific changes in the muscles of the left atrium that increased stroke risk in some of the volunteers. These changes were not associated with age or other risk factors for stroke. This could help many people with this condition to avoid taking warfarin or other clot-preventing medications for life. But it is much too early to include MRI as part of the standard evaluation of people with atrial fibrillation — not to mention that such scans would significantly increase the cost of these evaluations. For now, doctors will continue to use standard tools to help determine stroke risk.

Ask the doctor: I have a cataract but can still see well enough to drive. Should I have surgery?

Q. I'm 82 and a landscape painter. Lately the sight in my right eye seems to be affecting my painting, although I can still see well enough to read small print and drive. I have a cataract in that eye. Should I have cataract surgery?

A. A cataract is a thickening and cloudiness of the lens of the eye that is more common as we age. If your eye doctor has recommended that you have the cataract removed, then yes, you should have the surgery, especially if your vision is impaired. The surgery involves taking your lens out and replacing it with an artificial one. Being able to see more clearly will not only help your painting, but it will also reduce your risk of falling. There is even some evidence that people who have cataracts removed live longer than those who don't, possibly because their improved vision allows them to participate more fully in life.

Harvard researchers headline conference on gene editing

Harvard scientists are getting international attention for their work with breakthrough technology that can edit genes in living cells. Five Harvard experts—Dr. George Church of Harvard Medical School, and Drs. Keith Joung, David Liu, Kiran Musunuru, and Derrick Rossi, all of Harvard University—were featured speakers in the first-ever CRISPR Congress, held in Boston in February 2015. CRISPR stands for clustered regularly interspaced short palindromic repeats. These are segments of genes that contain repeating sequences of DNA.

The Harvard experts spoke to other scientists about CRISPR, which holds the potential to repair gene mutations, fight disease, and improve food supplies. Harvard researchers have demonstrated that CRISPR may be able to lower cholesterol levels, correct gene mutations, and block HIV infection. "Suddenly anyone can edit any piece of any DNA a thousand times more easily and precisely than before, which is game-changing for gene therapies, organ transplantation, aging reversal, and malaria," says Dr. Church.

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