Sexually transmitted infections (STIs) Archive

Experts say there's little evidence that low-dose aspirin therapy brings benefits, and there are some risks.

In recent years, there's been a lot of talk about the potential benefits, and risks, of a regular regimen of low-dose aspirin. While much of the discussion has centered on whether taking low-dose aspirin can head off cardiovascular disease, some of the focus has also been on breast cancer. Can regular doses of this over-the-counter pain reliever reduce your risk of this common cancer?

For a while there were hints that the evidence was leaning that way. Back in 2017, this area of research, while still inconclusive, was somewhat promising. For example, a 2017 study published in Breast Cancer Research found that among some 57,000 women, those who reported taking low-dose aspirin (81 mg) at least three times a week had a 16% lower risk of breast cancer over all and a 20% lower risk of a specific type of hormonally driven breast cancer.

Research we're watching

If you're looking forward to having some extra downtime after retirement, just make sure it doesn't bring more sitting-down time. A study published online Nov. 17, 2020, by the journal Occupational and Environmental Medicine found that on average, women saw a sharp increase in sedentary time — more than an additional 20 minutes each day — after they retired compared with when they were working. This is an unhealthy pattern that can lead to a higher risk for cardiovascular disease.

Researchers identified this trend by looking at data on nearly 700 people (nearly 85% of them women) from a Finnish study. Most of the participants worked in administrative roles or held professional positions before retiring at an average age of 63. To provide objective measurements of activity, the participants wore activity monitors continuously for a full week during their one or two years both before and after retirement. The spike in sedentary time occurred after retirement, and remained at the reduced level for the next two years or more following retirement. Men, by contrast, saw a gradual decline in their activity level over time, but no sudden spike after they left their jobs. So, if you're retiring in the near future, it may be worth keeping an eye on your activity level to make sure you don't slow down after you leave your job.

Make your remaining years the best possible with these strategies.

There's a saying: "The trouble is, you think you have the time." People may understand their lives are limited, but they often don't internalize how much time they actually have left. This mindset can delay goal setting and long-term preparation, which increases the chances of later problems — for instance, with finances, housing, or health.

"People don't like to talk about their mortality because they don't want to see themselves as 'old,'" says Joan Gillis, a geriatric clinical social worker and senior clinical team manager with Harvard-affiliated McLean Hospital. "But embracing this reality can help people grasp a sense of urgency, so they get the most from their remaining years."

Gout, a debilitating form of arthritis, is on the rise compared with rates in prior decades. Obesity is probably a significant factor in this increase. Now, a new study suggests that three-quarters of gout cases in men might be completely avoidable by following certain protective health habits.

Falls rank among the top causes of death and injuries among the elderly, and the risk increases significantly in older people being treated for cancer. Now, investigators are reporting that a newer class of drugs for advanced prostate cancer is associated with a significant increase in fall risk. Called androgen receptor inhibitors, or ARIs, these […]

The pandemic may be making life harder for those in abusive relationships, but help is available.

A woman experiencing abuse at the hands of an intimate partner often feels isolated and alone. But the truth is, she has a lot of company. As many as one in three women in the United States has experienced intimate partner violence (IPV), which is violence involving a current or former spouse, partner, significant other, boyfriend or girlfriend, says Eve M. Valera, an associate professor in psychiatry at Harvard Medical School. This number includes women from all different ages and backgrounds.

Those who experience IPV may be left with lingering health effects, including mental health disorders such as anxiety, depression, or post-traumatic stress disorder. IPV is also linked to a number of physical symptoms and conditions, according to the federal Office on Women's Health, such as digestive problems, migraine headaches, arthritis, asthma, chronic pain, sexual problems, and heart problems. Another area of growing concern for many researchers is the potential for cognitive changes caused by traumatic brain injuries linked to abuse, says Valera.

Research we're watching

Can your current or past menstrual cycle offer clues about your longevity? A study published Oct. 3, 2020, in The BMJ linked irregular or long menstrual cycles (defined as 40 days or more) throughout adolescence and adulthood to a higher risk of early death (before age 70), compared with that seen in women who had normal or short menstrual cycles. The study authors, who used data from nearly 80,000 women who participated in the Nurses' Health Study II, found that the association was stronger for deaths from heart and blood vessel disease and in women who smoked.

Women in the study were, on average, 38 years old and had no history of cardiovascular disease, cancer, or diabetes when the study began. Researchers asked them to recall the regularity and length of their menstrual cycles at various times in their life. The researchers followed the women for 24 years, noting deaths from various causes over time. The association of early death with irregular or long menstrual cycles persisted even after they corrected for other factors, such as lifestyle and family history.

New calculators can estimate the chance your cancer might — or might not — become more aggressive.

Active surveillance is a popular option for men with low-risk prostate cancer, defined as a tumor that is confined to the prostate gland and unlikely to grow or spread. It involves monitoring prostate-specific antigen (PSA) levels in the blood for changes and having regular digital rectal exams to look for abnormal areas on your prostate.

During active surveillance, you have a PSA test and a digital rectal exam every six months and prostate biopsies approximately every other year. If your PSA level rises, your doctor will likely recommend a prostate MRI or an immediate prostate biopsy to see if the cancer has become more aggressive. If so, you and your doctor can decide whether to continue with active surveillance and have another biopsy six months or a year later, or move ahead to treatment, such as radiation, hormonal therapy, or surgery.