Mental Health Archive

Research we're watching

According to a study published in the Aug. 4, 2020, issue of Neurology, the number of new cases of dementia in Europe and North America has dropped 13% every 10 years over the past 30 years. Researchers looked at data collected by the Alzheimer's Research Consortium, which included people over age 65 in Europe and the United States.

The actual number of adults with dementia has increased dramatically in recent years as life expectancy increases. The condition currently affects some 47 million people worldwide, and that number is expected to increase in coming decades.

Contrary to conventional wisdom, some blood pressure drugs are linked to a lower risk of depression.

Like all medications, blood pressure drugs sometimes cause unwanted side effects. While many are mild and short-lived, some are more worrisome, including mood changes such as depression. But contrary to what doctors have long assumed, blood pressure drugs may not raise the risk of depression. In fact, some appear to be linked to a lower risk, according to a recent study (see "Depression rates in people taking different blood pressure drugs").

"The traditional view has been that blood pressure drugs that cross the blood-brain barrier are more likely to cause depression," says Dr. Randall -Zusman, a cardiologist at Harvard-affiliated Massachusetts General Hospital. Depression has also been associated with drugs known as beta blockers. But beta blockers (which work in part by slowing the heart rate) can also make you feel tired and listless, which may dampen your mood, Dr. Zusman explains.

The pandemic has made it especially hard for people with persistent depressive disorder.

Almost everyone goes through rough mental patches. You may feel down, sad, and lethargic. Most people bounce back with no problem, but if these feelings become more frequent and linger longer, you could have a mild, yet still serious form of depression called persistent depressive disorder (PDD), also known as dysthymia.

Older adults are especially vulnerable to PDD, and more so during the COVID-19 pandemic, says Dr. David Mischoulon, a psychiatrist at Harvard-affiliated Massachusetts General Hospital. "While the COVID pandemic affects everyone, older adults have experienced increased stressors like economic issues, prolonged isolation, and the threat of getting sick, all of which can trigger feelings of anxiety and depression beyond the norm."

The condition is an all-too-real problem for men, and one of the more difficult to treat.

After age 50, men often have periods of discomfort "down there." It could be a cramping, aching, or throbbing pain in and around your pelvis and genitals. You also may have issues in the bedroom and bathroom. While the problems are real, the cause is often difficult to pinpoint.

It's called chronic pelvic pain syndrome (CPPS) — also known as chronic prostatitis — and it's one of the most puzzling and difficult-to-manage conditions for older men.

This year has been extremely stressful for everyone, and that stress can lead to harmful habits. For those working to stay in recovery from an addiction, the challenge is even more profound. Those in this situation know that the more stressful things are, the more important it is to practice the healthy habits that sustain recovery.

Endometriosis occurs in women when tissue similar to the lining of the uterus grows in other places in the body, most commonly within the pelvis, causing pain and other symptoms. Many women with this condition are not diagnosed properly until middle age. There are several options for treatment, and it may take time to find what works best for each person.

In the journals

Researchers are close to finding early cancer with a blood test. They may soon do the same with Alzheimer's disease. A new blood test called p-tau217 has shown great promise in diagnosing people with the disease, according to findings published online July 28, 2020, by JAMA.

The test looks for a specific type of tau protein in the blood. In people with Alzheimer's, tau protein in the brain forms tangles. Accumulation of tau protein tangles along with beta-amyloid deposits is thought to play a key role in how the disease develops.

Here's how to cope when your usual traditions get uprooted.

The holiday season, like just about everything else this year, probably won't look the same as usual. Whether that means going to smaller gatherings without the usual relatives, quarantining when traveling, or staying home entirely, chances are something will be different this year thanks to the COVID-19 pandemic. For many who look forward to a full table at Thanksgiving or a big party on New Year's Eve, these changes are unwelcome, and frankly a little depressing.

In response, people may experience emotions ranging from guilt to loneliness to a feeling of disconnected sadness, says Dr. Hilary Connery, assistant professor of psychiatry at Harvard Medical School.

Research we're watching

Doctors have long known that mental or psychological stress can lead to angina (chest pain or discomfort caused by inadequate blood to the heart). Now, new research reveals a direct correlation between angina and stress-related activity in the brain's frontal lobe. The study included 148 people with coronary artery disease with an average age of 62. All underwent brain and heart imaging tests done in conjunction with mental stress testing, which involved mental arithmetic and public speaking. Imaging tests were also done under "control" conditions, which featured simple counting and recalling a neutral event. Researchers monitored the participants for angina during the tests; they also assessed angina rates again after two years.

Activity in the inferior frontal lobe area of the brain during mental stress was linked to the severity of self-reported angina, both during the brain imaging and at the two-year follow-up. A better understanding of how the brain reacts to stress may be an important consideration for doctors who treat angina, according to the study's lead author. The study was published online Aug. 10, 2020, by the journal Circulation: Cardiovascular Imaging.

Intimate partner violence can occur between people of any gender or sexual orientation. Abuse can leave people feeling isolated, confused, or hopeless, and talking to a health professional is one way to get help in the form of medical treatment or access to appropriate services.