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A new hormonal therapy for prostate cancer is under expedited FDA review

In June, the US Food and Drug Administration (FDA) launched an accelerated review of a promising new drug for advanced prostate cancer. Called relugolix, it suppresses testosterone and other hormones that speed the cancer’s growth. If approved, this new type of hormonal therapy is expected to set a new standard of care for the disease. […]

The no-drug approach to erectile dysfunction

There are ways to manage ED without medication.

Erectile dysfunction (ED) is one of the more common health issues older men face, especially those with cardiovascular disease and diabetes. Some estimates suggest between 50% and 70% of men ages 50 to 70 experience mild to moderate ED.

ED is defined as difficulty achieving or sustaining an erection. It is often caused by a combination of physical and emotional issues. ED makes intercourse difficult, which can lower sex drive and desire, increase anxiety and depression, and affect a man's relationship with his partner.

Combining two types of biopsies helps diagnose prostate cancer

In the journals

Combining two kinds of biopsies may lead to a more accurate diagnosis of prostate cancer, suggests a study in the March 5, 2020, issue of The New England Journal of Medicine. Researchers from the National Cancer Institute enrolled 2,103 men with prostate abnormalities. Each man had a standard 12-point biopsy and an MRI-targeted biopsy.

With a 12-point biopsy, tissue samples are taken from 12 systematically placed spots on the prostate. An MRI-targeted biopsy uses an MRI image of the prostate to help doctors locate areas where cancer is most highly suspected. Previous research has shown that MRI-targeted biopsies are more accurate than 12-point biopsies. However, even MRIs can miss some tumors.

New drugs approved for advanced BRCA-positive prostate cancer

Defective BRCA genes are well known for their ability to cause breast and ovarian cancers in women. But these same gene defects are also strong risk factors for aggressive prostate cancer in men. About 10% of men with metastatic prostate cancer — meaning cancer that is spreading away from the prostate — test positive for […]

The facts about testosterone and sex

Can boosting testosterone levels improve your sex life?

The hormone testosterone plays a big part in men's health, but perhaps its most meaningful role is to fuel sex drive and performance.

Testosterone levels tend to decrease with age. They peak by early adulthood and then can drop by up to 1% per year beginning around age 40. Sometimes an abrupt fall occurs because of an injury or illness (such as an infection), chemotherapy or radiation treatment, or certain medications.

Combining different biopsies limits uncertainty in prostate cancer diagnosis

Are prostate cancer biopsies reliably accurate? Not always. The most common method, called a systematic biopsy, sometimes misses tumors, and it can also misclassify cancer as being either more or less aggressive than it really is. During systematic biopsy, a doctor takes 12 evenly-spaced samples of the prostate, called cores, while looking at the gland […]

Some healthcare can safely wait (and some can’t)

Some routine or elective healthcare can safely wait a while, but putting off medical care for certain health conditions or potentially serious problems is risky.

All rise now — just how fit are you?

Attempting to stand up from a seated position on the floor is a good way to assess your overall fitness. No problem? Do it regularly to track your physical health. Having difficulty? Try these exercises to help you improve your fitness.

Can vitamin and mineral supplements protect against prostate cancer?

On call

Q. Can specific types of supplements help reduce my risk of developing prostate cancer?

A. Most studies of vitamin and mineral supplements have had disappointing results. In fact, some even appear to increase prostate cancer risk. Here's a rundown on where everything stands.

The dating game

How older men can approach the dating life again — and why they should.

One downside to aging is the higher likelihood that at some point you will not have a partner. No matter what the reason for your singlehood, a healthy remedy is to begin dating again.

"Pursuing a more robust social and romantic life is good medicine for your mental and physical health," says Dr. Sharon Bober, founding director of the Sexual Health Program at Harvard-affiliated Dana-Farber Cancer Institute.

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