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Combining two types of biopsies helps diagnose prostate cancer

In the journals

Combining two kinds of biopsies may lead to a more accurate diagnosis of prostate cancer, suggests a study in the March 5, 2020, issue of The New England Journal of Medicine. Researchers from the National Cancer Institute enrolled 2,103 men with prostate abnormalities. Each man had a standard 12-point biopsy and an MRI-targeted biopsy.

With a 12-point biopsy, tissue samples are taken from 12 systematically placed spots on the prostate. An MRI-targeted biopsy uses an MRI image of the prostate to help doctors locate areas where cancer is most highly suspected. Previous research has shown that MRI-targeted biopsies are more accurate than 12-point biopsies. However, even MRIs can miss some tumors.

New drugs approved for advanced BRCA-positive prostate cancer

Defective BRCA genes are well known for their ability to cause breast and ovarian cancers in women. But these same gene defects are also strong risk factors for aggressive prostate cancer in men. About 10% of men with metastatic prostate cancer — meaning cancer that is spreading away from the prostate — test positive for […]

The facts about testosterone and sex

Can boosting testosterone levels improve your sex life?

The hormone testosterone plays a big part in men's health, but perhaps its most meaningful role is to fuel sex drive and performance.

Testosterone levels tend to decrease with age. They peak by early adulthood and then can drop by up to 1% per year beginning around age 40. Sometimes an abrupt fall occurs because of an injury or illness (such as an infection), chemotherapy or radiation treatment, or certain medications.

Combining different biopsies limits uncertainty in prostate cancer diagnosis

Are prostate cancer biopsies reliably accurate? Not always. The most common method, called a systematic biopsy, sometimes misses tumors, and it can also misclassify cancer as being either more or less aggressive than it really is. During systematic biopsy, a doctor takes 12 evenly-spaced samples of the prostate, called cores, while looking at the gland […]

Some healthcare can safely wait (and some can’t)

Some routine or elective healthcare can safely wait a while, but putting off medical care for certain health conditions or potentially serious problems is risky.

All rise now — just how fit are you?

Attempting to stand up from a seated position on the floor is a good way to assess your overall fitness. No problem? Do it regularly to track your physical health. Having difficulty? Try these exercises to help you improve your fitness.

Can vitamin and mineral supplements protect against prostate cancer?

On call

Q. Can specific types of supplements help reduce my risk of developing prostate cancer?

A. Most studies of vitamin and mineral supplements have had disappointing results. In fact, some even appear to increase prostate cancer risk. Here's a rundown on where everything stands.

The dating game

How older men can approach the dating life again — and why they should.

One downside to aging is the higher likelihood that at some point you will not have a partner. No matter what the reason for your singlehood, a healthy remedy is to begin dating again.

"Pursuing a more robust social and romantic life is good medicine for your mental and physical health," says Dr. Sharon Bober, founding director of the Sexual Health Program at Harvard-affiliated Dana-Farber Cancer Institute.

Behavioral therapy can relieve overactive bladder symptoms

In the journals

Men often rely on drugs to manage overactive bladder symptoms, such as frequent urination, urgency, incontinence, and nocturia (having to use the bathroom at night). However, a study published online Jan. 13, 2020, by JAMA Internal Medicine suggests that adding behavioral therapy may lead to better results.

Scientists recruited more than 200 men (average age 64) with overactive bladder symptoms and divided them randomly into three groups. One group received only drug therapy. One received only behavioral therapy, which consisted of learning pelvic floor exercises and relaxation techniques to help suppress urges and prevent urine loss. The third group had both behavioral and drug therapy.

New radiation therapies keep advanced prostate cancer in check

Treatments for prostate cancer are always evolving, and now research is pointing to new ways of treating a cancer that has just begun to spread, or metastasize, after initial surgery or radiation. Doctors usually give hormonal therapies in these cases to block testosterone, which is a hormone that makes the cancer grow faster. But newer […]

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