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Libido and sexual performance Archive

Medications and treatments

Is your medication killing your sex drive?

Updated May 19, 2026

Low libido can include both less desire for and less satisfaction with sex. A variety of medications can dampen sex drive by altering hormone levels or nerve signals, dulling sensation in the genitals, or triggering fatigue or mood changes. They include some antidepressants, cardiovascular drugs, antihistamines, antiseizure drugs, opioids, chemotherapy, hormone blockers, oral contraceptives, and fertility drugs. People whose medications affect their libido can ask their doctor to adjust the dose or timing or substitute another drug without sexual side effects.

Men's Health

Why testosterone levels drop and when to consider treatment

Published March 27, 2026

Low libido, erectile dysfunction, fatigue, reduced muscle mass, hot flashes, and more may be symptoms of testosterone deficiency. Testing can help determine the diagnosis, and testosterone replacement therapy may help counter the decline in the hormone.

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