Immune and infectious diseases Archive

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A long-used vaccine is showing promise in helping to restore near-normal blood sugar levels in people with advanced type 1 diabetes. Researchers from Harvard Medical School injected adults who had type 1 diabetes with two doses of the bacillus Calmette-Guérin (BCG) vaccine, which is traditionally used to prevent tuberculosis.

Participants in the study, all of whom had type 1 diabetes for many years, all showed significant improvements in their average blood sugar levels after the vaccination. The improvements lasted for the next five years. Researchers said that it appears the vaccine affected a metabolic mechanism that increases consumption of glucose by cells.

Antibiotics are crucial tools in fighting illnesses, but over-reliance on them can have serious consequences. A new study found that babies who were given antibiotics in their first two years were significantly more likely to become obese.

Most people who get Lyme disease recover after a course of antibiotics, but some patients continue to experience symptoms for months or even years. There is much controversy around post-treatment Lyme disease, particularly in how long patients should continue taking antibiotics.

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Baby boomers are falling short in getting hepatitis C screenings. In 2012, the CDC urged the entire generation of people born from 1945 to 1965 to get this simple blood test, noting that baby boomers are five times more likely to have the virus than other adults. But a study published online March 27, 2018, by the journal Cancer Epidemiology, Biomarkers & Prevention found that only about 13% of baby boomers had been tested by 2015, up just one percentage point from 2013. The information came from national government health surveys. Hepatitis C can lead to cirrhosis, liver damage, liver cancer, and liver failure. Treatments are now available that can cure hepatitis C, if it's caught early enough. Baby boomers are believed typically to have become infected in the 1960s through the 1980s, when transmission of hepatitis C was highest. People at highest risk are those who have used intravenous drugs, had more than one sex partner, or received a blood transfusion before 1992, when the blood test for hepatitis C was first available.

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The number of annual cases of Lyme disease in the United States nearly doubled from 2004 to 2016 (and those are just the reported cases), but several other serious illnesses can be spread by ticks and mosquitoes.