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Immune and infectious diseases Archive

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A vaccine that can prevent shingles

The best way to avoid shingles and long-lasting pain that may result from it is to get the shingles vaccine (Shingrix), given in two doses. The vaccine contains a protein from a dead varicella-zoster virus. The shot is 90% effective and is recommended for adults ages 50 or older, even those who have had shingles before, received an older shingles vaccine called Zostavax, or don’t recall having had chickenpox. People should avoid the vaccine if they currently have shingles, are allergic to components of the vaccine, or are pregnant or breastfeeding.

7 strategies to prevent cancer

Making healthy lifestyle changes can prevent an estimated 40% of cancers. These include eating a healthy diet, exercising regularly, getting adequate sleep, and maintaining a healthy body weight. People can also help prevent cancers by seeking recommended cancer screenings. Some screenings merely identify cancers early, but others, such as colonoscopies and Pap tests, can find precancerous conditions and are actually able to prevent cancer.

Chronic gut inflammation: Coping with inflammatory bowel disease

Chronic inflammation in the gut may be due to inflammatory bowel disease, such as Crohn’s disease or ulcerative colitis. It’s unclear what causes IBD. Doctors suspect it’s a combination of factors, such as eating an unhealthy diet or using certain medications; altered gut bacteria; having a leaky gut; or genetics. The goal of IBD treatment is remission: suppressed symptoms, lower blood levels of inflammatory markers, and normal-looking bowel and tissue biopsies. Approaches to achieve remission and prevent flare-ups include medication, a healthy lifestyle, and possibly surgery.

New information for parents on myocarditis and COVID-19 vaccines

Reports of young people developing myocarditis and pericarditis after getting one of the mRNA vaccines for COVID-19 have made some parents reluctant to get their children vaccinated. It's understandable to worry about such a side effect, but before choosing not to vaccinate, it's important to look at the whole picture.

Autoimmune conditions and heart disease

People with systemic inflammatory conditions such as rheumatoid arthritis, lupus, and psoriasis are more likely to have heart attacks and to die of cardiovascular disease than people in the general public. The 2019 expert guidelines for preventing heart disease says these conditions should be considered "risk enhancers" when estimating heart attack risk. But this added risk may be underrecognized and undertreated.

Thoughts on optimism

Science continues to find that people with an optimistic outlook enjoy healthier and longer lives. The power of optimism is not just having a sunny disposition, but applying this mindset to make positive change. Even if people are not naturally optimistic, there are ways to change one’s outlook, such as looking for opportunities during trying times, focusing on personal strengths, practicing gratitude, and visualizing their best possible self.

Chronic inflammation and your joints

The immune system sometimes launches a chronic inflammatory response in certain joints. That leads to pain, stiffness, and joint damage known as inflammatory arthritis. It’s usually unknown what triggers the conditions. Types of inflammatory arthritis include rheumatoid arthritis, gout, and psoriatic arthritis. Treatments include medications, such as biologic or nonbiologic disease-modifying antirheumatic drugs (DMARDs), and lifestyle habits, such as exercising, avoiding processed foods, reducing stress, not smoking, and getting enough sleep. Wearing a splint or brace on affected joints and seeking physical therapy may also help ease pain.

COVID-19 and cardiovascular concerns: An evolving story

Physicians’ understanding of how a COVID-19 infection affects the heart is still evolving. More definitive answers require long-term, randomized clinical trials that control for different factors (including varied medical histories and medication use) to study how COVID-19—and possible therapies—affect people who have or are at risk for heart disease. Like other infectious organisms, SARS-CoV-2 (the virus that causes COVID-19) can increase the risk of blood clots and may damage the heart, but the danger is less common than initial reports suggested.

Adjusting gut bacteria may improve response to cancer treatment

Gut bacteria may play a role in response to cancer treatments that target the immune system.

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