Mind & Mood Archive

Asking for help from friends and family and then engaging with your new community will get you through the transition.

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Downsizing from a large home to a smaller one is a fact of life for many older adults. The reason may be finances, health issues, or a desire to simplify your lifestyle. But making the transition can bring a host of emotions: sadness, grief, stress, or anxiety.

Understanding the triggers for these feelings and using strategies to navigate them may not change how you feel, but it may help the downsizing process go more smoothly so you can focus on your next chapter.

Research we're watching

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A new study published online June 21 by the journal Neuron links two common viruses to Alzheimer's disease. Based on data from three brain banks, researchers found that the brains of people with Alzheimer's disease had up to twice the levels of two viruses — herpesviruses 6A and 7 — compared with the brains of people who did not have dementia. The virus genes also appeared to have interacted with the human DNA in cells in the brain in ways that might have affected Alzheimer's disease risk.

Infection with these herpesviruses is very common. Up to 90% of people may be exposed to these viruses in childhood. They cause, among other things, a mild infection known as roseola, which produces a rash and a fever.

News briefs

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An observational study published online May 30, 2018, by JAMA Psychiatry found that engaging in intellectually stimulating activities, even later in life, may lower the odds of dementia. Researchers followed over 15,000 Chinese men and women in their 70s for seven years with annual assessments of health and lifestyle habits, including a variety of leisure activities. The odds of being diagnosed with dementia during the study period were 29% lower in people who challenged their brains daily with such activities as playing board games, reading, and even betting on horse racing. In contrast, less mentally demanding recreational activities (like watching TV or shopping) or social activities (like going to tea with friends) did not appear to be associated with a lower risk of dementia. Other studies have found similar evidence, but this one made a special effort to adjust for factors like better overall health that might otherwise account for the association between brain exercise and dementia.

In the journals

Anticholinergic medications used to treat bladder conditions, Parkinson's disease, and depression are associated with an increased risk of dementia, according to a large study published online April 25, 2018, by The BMJ. Anticholinergic drugs help to contract and relax muscles. They work by blocking acetylcholine, a substance that also transmits messages in the nervous system. In the study, researchers compared the medical records of 40,770 people older than 65 who were diagnosed with dementia and 283,933 seniors without.

They found that people diagnosed with dementia were up to 30% more likely to have been prescribed anticholinergic medications for Parkinson's, bladder problems, or depression. Frequently prescribed anticholinergic drugs include procyclidine (Kemadrin) for Parkinson's; tolterodine, oxybutynin, and solifenacin (Vesicare) for urological conditions like overactive bladder or incontinence; and amitriptyline, dosulepin, and paroxetine for depression. However, there was no association between dementia and anticholinergic drugs used to treat other common conditions like hay fever, travel sickness, and stomach cramps.

In the journals

Aerobic exercise has been linked with reducing symptoms of depression, but resistance training, such as weight lifting and bodyweight exercises like push-ups, can have the same effect.

A meta-analysis published in the June 2018 JAMA Psychiatry examined the effects of resistance training on depression symptoms in 33 clinical trials involving 1,877 people. The researchers found that people who did this type of exercise reported a significant reduction in such symptoms as low mood, loss of interest in activities, and feelings of worthlessness, compared with those who did not exercise.

Research we're watching

If you're able to quickly shrug off stressful events, that may be good for your health. A study in the March 19 issue of Psychological Science found that people who held on to stress—those who reported still having negative feelings about a stressful event the day after it happened — had more chronic health problems a decade later.

Researchers analyzed data from a nationwide survey that asked more than 1,100 adults about the number and type of stressful experiences they had each day for eight days. These included everything from arguments with others to problems at work, home, or school. Participants rated their emotional reactions to these stressors at the time and afterward.

Mindfulness is the practice of purposely focusing your attention on the present moment, such as how the air smells and feels as you walk your dog, or how a bite of bread tastes with dinner. The ultimate goal is to help shift your thoughts away from your usual preoccupations toward an appreciation of the moment and a larger perspective on life.

Scientific examination of mindfulness shows that it can improve both physical and psychological symptoms and create positive changes in health attitudes and behaviors.

Strengths are built-in capacities for certain thoughts, feelings, and behaviors. Everyone has these capacities to one degree or another. Your particular pattern of strengths is part of what makes you unique.

When you play from your strengths, you are likely to feel more energetic and perform better than when you are trying to use a capacity that comes less naturally. For example, one person trying to influence a local school board to ban soft drink sales might have the strength to speak up forcefully and clearly at a general meeting (despite the almost-universal fear of public speaking). Another person strong in team-building might feel uncomfortable speaking out in a meeting but could successfully build consensus among parents, nutritionists, and others to weigh the issue and come to a decision.

Mind-body medicine is providing new models for wellness and therapy by combining conventional and complementary approaches to treatment. At this seminar, a panel of Harvard Medical School faculty will discuss this quickly developing approach that may help shape the future of medicine.

Each spring, Harvard Medical School's Office of Communications and External Relations organizes a series of four free "mini-med school" classes for the general public in the heart of Boston's Longwood Medical Area. At the end of the seminar series, participants who attend three out of the four sessions receive a certificate of completion. Topics are selected for their appeal to a lay audience and have included the human genome, nutrition, sleep dynamics and health care access. Faculty from Harvard Medical School and its affiliate hospitals volunteer their time to present these lectures to the community.