Mind & Mood Archive

A study published in JAMA in July 2024 found that a blood test was accurate in diagnosing Alzheimer's disease, which causes steep declines in cognition and other aspects of health. The blood test is able to detect elevated blood levels of brain proteins that characterize the condition. While that's progress, doctors say it's not the test needed most. It would be more beneficial, they say, to have a test that accurately spots the developing disease long before it affects thinking. No such tests are here yet, but scientists are working to develop them.

A 2024 study involving more than 149,000 people, middle-aged and older, found that those who had shingles were 20% more likely to notice signs of cognitive decline years later, compared with those who didn't have shingles.

In a 2024 study of 900 dementia-free older adults, those who developed mild cognitive impairment had lower levels of life purpose and personal growth years before a diagnosis, compared with those whose thinking skills remained sharp.

Prolonged grief disorder (PGD) involves 12 months or longer of debilitating grief. An estimated 7% to 10% of bereaved people experience PGD. Signs include feeling as though part of you has died, marked sense of disbelief about the death, denial or immense difficulty accepting the loss, extreme loneliness, and feeling that life is meaningless. People who are more vulnerable to PGD include women in general as well as people who lost a loved one in a traumatic or unexpected way, lost a child, or have coped with anxiety or depression. Treating PGD may involve a blend of therapies.

Men can encounter episodes of depression and anxiety as they age. Such feelings often stem from life experiences like grief, financial anxiety, health issues, and the loss of independence. While confiding in friends and family can sometimes help, men may benefit more from therapy. A professional therapist can help identify the causes of their emotional problems and create a strategy to resolve them.

Meditation helps us calm the body and shift perspective, and certain types of it offer an array of health benefits. What's more, imaging research shows that meditation can change the structure and connectivity of brain areas to help us cope with fear and anxiety.

When ADHD persists through early adulthood into middle age, it presents many of the same challenges it does in childhood, but with added pressures from the busier pace of life and expectations from work and family. Fortunately there are strategies that can help you navigate this condition.

In addition to hallmark symptoms such as persistent sadness and apathy, depression can also trigger memory problems. People with depression may lack focus, leading to memory lapses. Depression may also alter brain chemicals that help people sustain attention. Memory problems in depression show up differently than in dementia, making people unable to retrieve long-term memories. Positive memories also fade first in depression because brain areas that process positive or rewarding experiences are disrupted.