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Decoding rheumatoid arthritis

Rheumatoid arthritis (RA) affects two to three times as many women as men. Scientists are uncovering RA's potential genetic and hormonal underpinnings, which point to potential reasons why women are more vulnerable. The newest treatments, called Janus kinase (JAK) inhibitors, resulted from research that has teased out delicate differences in immune system pathways. They block numerous proteins that ramp up inflammation fundamental to RA. The wide array of drug options now available for RA help doctors personalize therapies to each patient.

No cognitive effects seen after years of very low LDL cholesterol

Having an extremely low LDL level from aggressive cholesterol-lowering therapy was not associated with cognitive impairment, according to a 2024 study.

When pills pose problems

Up to 40% of American adults have reported difficulty swallowing pills. Older adults are more susceptible to this problem, known as dysphagia, because they take more medications. Dysphagia may provoke people to abandon their medication regimen. Problems swallowing pills are typically traceable either to the medication or the person taking it. Drugs can cause dry mouth, affect taste, irritate the esophagus, or cause sedative effects. Conditions that affect swallowing include cancer, stroke, neurological diseases, and hiatal hernia.

Are you taking too many medications?

Many people need to take multiple medications for health and symptom control, but it requires extra attention to prevent risks for drug interactions, dosage errors, and other problems. Several strategies can help, such as learning the names of pills, what they do, and why they're necessary; writing down the day, time, and dose of each drug; using organization tools such as pillboxes and alarms; and scheduling a medication review with a doctor or pharmacist every 12 months, so that unnecessary pills-such as those no longer needed-can be omitted.

What are the risks from taking statins?

The two main side effects caused by statins are muscle aches (which disappear once the drug is stopped) and a higher risk of diabetes (which is most common in people with obesity and prediabetes).

These drugs might be best to relieve migraine pain

A 2024 analysis of 137 studies involving almost 90,000 people found that older drugs called triptans are more effective at stopping migraine pain in a moment of agony, compared with newer medications such as ditans and gepants.

Think your child has ADHD? What your pediatrician can do

Problems with attention and focus, impulsivity, and constant motion are possible symptoms of ADHD.

New surgery for benign prostate hyperplasia provides long-lasting benefits

Most men over 50 will develop an enlarged prostate. Many different therapies are available, including medications and various types of surgery. Aquablation is gaining in popularity, and a recent study showed that improvements in urinary function from aquablation were still holding up after five years.

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