Heart Disease Archive

Research we're watching

People with low HDL (good) cholesterol and high triglycerides may be more likely to be hospitalized for pneumonia, according to a study in the Aug. 15, 2020, American Journal of Medicine.

The study included more than 13,000 people who were part of a long-term study designed to look at lipids and other factors linked to heart disease. Using hospital discharge records, researchers found that nearly 15% of the participants had been hospitalized with pneumonia during the follow-up, which lasted a median of 21 years.

Research we're watching

A drug made from a highly purified form of EPA (an omega-3 fatty acid found in fish) appears to help reduce plaque in the heart's arteries, according to a study published online Aug. 29, 2020, by the European Heart Journal. The findings may explain why the drug, icosapent ethyl (Vascepa), lowers the risk of heart attack and stroke by 26% in people at high risk for those serious problems.

The study included 80 people with fatty plaque in the arteries of the heart (coronary artery disease). Most of them had diabetes and were taking a statin. Their trigly­cerides were elevated, ranging from 135 to 499 milligrams per deciliter. Half were randomly assigned to take 4 grams of icosapent ethyl daily; the other half received a placebo.

Drinking no more than four or five 8-ounce cups of coffee per day—equal to about 400 milligrams of caffeine—helps people get the drink's health benefits with a lower risk of caffeine side effects like anxiety and nervousness.

Research we're watching

Eating a daily serving of cabbage, cauliflower, broccoli, or brussels sprouts is linked to a lower likelihood of harmful calcium buildup in the aorta, the body's largest artery, according to a new report.

The study featured 694 older Australian women who were initially enrolled in a study looking at diet, supplements, and bone fractures. The spine imaging tests used in the study also revealed the amount of calcification in the abdominal portion of the aorta. So researchers used those data to explore the link between diet and aortic calcification, a sign of plaque buildup (atherosclerosis) that leads to cardiovascular disease. The study, which was published online July 17, 2020, by the British Journal of Nutrition, found 46% lower odds of extensive abdominal aortic calcification among women who ate at least 45 grams of cruciferous vegetables daily (equal to one serving; about a half-cup) as compared with women who ate less than 15 grams of cruciferous veggies a day. The vegetables contain substances such as fiber that help discourage atherosclerosis.

Research we're watching

Doctors have long known that mental or psychological stress can lead to angina (chest pain or discomfort caused by inadequate blood to the heart). Now, new research reveals a direct correlation between angina and stress-related activity in the brain's frontal lobe. The study included 148 people with coronary artery disease with an average age of 62. All underwent brain and heart imaging tests done in conjunction with mental stress testing, which involved mental arithmetic and public speaking. Imaging tests were also done under "control" conditions, which featured simple counting and recalling a neutral event. Researchers monitored the participants for angina during the tests; they also assessed angina rates again after two years.

Activity in the inferior frontal lobe area of the brain during mental stress was linked to the severity of self-reported angina, both during the brain imaging and at the two-year follow-up. A better understanding of how the brain reacts to stress may be an important consideration for doctors who treat angina, according to the study's lead author. The study was published online Aug. 10, 2020, by the journal Circulation: Cardiovascular Imaging.

Research we're watching

Serious heart complications are common in people hospitalized with influenza, according to a study published online Aug. 25, 2020, by Annals of Internal Medicine.

Researchers from the CDC looked at the rates of cardiovascular problems in more than 80,000 adults hospitalized with a confirmed case of influenza (commonly called the flu) from 2010 to 2018. Almost 12% had a serious cardiovascular problem, most commonly heart failure or a lack of adequate blood flow to the heart, known as acute coronary syndrome. The body's immune response against the infection can trigger inflammation and other changes that harm the cardiovascular system.